Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- OSLD (2)
- 4D imaging (1)
- 4D-CBCT (1)
- Angular dependence (1)
- Brachytherapy (1)
-
- Cone-beam CT (1)
- Dosimetry (1)
- GSBS (1)
- Gel dosimetry (1)
- HDR (1)
- High dose rate (1)
- IGRT (1)
- Image reconstruction (1)
- Inter play effect (1)
- LET (1)
- Linear energy transfer (1)
- Lung imaging (1)
- Medical imaging (1)
- OCT (1)
- OSL (1)
- Optical computed tomography (1)
- Optically stimulated luminescence dosimeters (1)
- Passive scattering (1)
- Pelvic phantom (1)
- Proton therapy (1)
- Protons (1)
- RPC (1)
- Radiation therapy (1)
- Radiological Physics Center (1)
- Radological Physics Center (1)
Articles 1 - 5 of 5
Full-Text Articles in Physics
Evaluation Of Polymer Gel Dosimeters For Measurements Of Dose And Let In Proton Beams, Kevin M. Vredevoogd
Evaluation Of Polymer Gel Dosimeters For Measurements Of Dose And Let In Proton Beams, Kevin M. Vredevoogd
Dissertations & Theses (Open Access)
This project assessed the effectiveness of polymer gel dosimeters as tools for measuring the dose deposited by and LET of a proton beam. A total of three BANG® dosimeter formulations were evaluated: BANG®-3-Pro-2 BANGkits™ for dose measurement and two BANG®-3 variants, the LET-Baseline and LET-Meter dosimeters, for LET measurement. All dosimeters were read out using an OCT scanner. The basic characteristics of the BANGkits™ were assessed in a series of photon and electron irradiations. The dose-response relationship was found to be sigmoidal with a threshold for response of approximately 15 cGy. The active region of the dosimeter, the volume in …
Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Dissertations & Theses (Open Access)
The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning uses models of tumor respiratory motion to account for target motion in targeting. The tumor motion model can be verified on a per-treatment session basis with four-dimensional cone-beam computed tomography (4D-CBCT), which acquires an image set of the dynamic target throughout the respiratory cycle during the therapy session. 4D-CBCT is undersampled if the scan time is too short. However, short scan time is desirable in clinical practice to reduce patient setup time. This dissertation presents the …
Development And Implementation Of A Remote Audit Tool For High Dose Rate (Hdr) 192ir Brachytherapy Using Optically Stimulated Luminescence Dosimetry, Kevin Casey
Dissertations & Theses (Open Access)
This work aimed to create a mailable and OSLD-based phantom with accuracy suitable for RPC audits of HDR brachytherapy sources at institutions participating in NCI-funded cooperative clinical trials. An 8 × 8 × 10 cm3 prototype with two slots capable of holding nanoDot Al2O3:C OSL dosimeters (Landauer, Glenwood, IL) was designed and built. The phantom has a single channel capable of accepting all 192Ir HDR brachytherapy sources in current clinical use in the United States. Irradiations were performed with an 192Ir HDR source to determine correction factors for linearity with dose, dose rate, …
Development And Implementation Of The Use Of Optically Stimulated Luminescent Detectors In The Radiological Physics Center Anthropomorphic Quality Assurance Phantoms, Jennelle Bergene
Dissertations & Theses (Open Access)
The Radiological Physics Center (RPC) uses both on-site and remote reviews to credential institutions for participation in clinical trials. Anthropomorphic quality assurance (QA) phantoms are one tool the RPC uses to remotely audit institutions, which include thermoluminescent dosimeters (TLDs) and radiochromic film. The RPC desires to switch from TLD as the absolute dosimeter in the phantoms, to optically stimulated luminescent dosimeters (OSLDs), but a problem lies in the angular dependence exhibited by the OSLD. The purpose of this study was to characterize the angular dependence of OSLD and establish a correction factor if necessary, to provide accurate dosimetric measurements as …
Verification Of The Clinical Implementation Of The Respiratory Gated Beam Delivery Technique With Synchrotron-Based Proton Irradiation, Yoshikazu Tsunashima
Verification Of The Clinical Implementation Of The Respiratory Gated Beam Delivery Technique With Synchrotron-Based Proton Irradiation, Yoshikazu Tsunashima
Dissertations & Theses (Open Access)
The clinical advantage for protons over conventional high-energy x-rays stems from their unique depth-dose distribution, which delivers essentially no dose beyond the end of range. In order to achieve it, accurate localization of the tumor volume relative to the proton beam is necessary. For cases where the tumor moves with respiration, the resultant dose distribution is sensitive to such motion. One way to reduce uncertainty caused by respiratory motion is to use gated beam delivery. The main goal of this dissertation is to evaluate the respiratory gating technique in both passive scattering and scanning delivery mode. Our hypothesis for the …