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Computational Fluid Dynamics In Small Airway Models Of The Human Lung, G. Burnside, J. R. Hammersley, Rama N. Reddy, B. Catlin

Journal of the Arkansas Academy of Science

The promise of gene replacement therapy for cystic fibrosis, the administration of drugs via inhalation therapy, and die deposition location of man-made airborne particulates all involve a more complete understanding of the fluid dynamics in the human lung. Flow in the larger airways may be measured through life-sized models directly, but the airways in the peripheral lung are too small and the flows are too complex to be studied in this manner. Computational models can be developed which will accurately represent both the geometric nature of the central airways and the fluid dynamics with in them. Two-dimensional and three-dimensional models …