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Full-Text Articles in Physics
Evolution Of Network Architecture In A Granular Material Under Compression, Lia Papadopoulous, James G. Puckett, Karen E. Daniels, Danielle S. Bassett
Evolution Of Network Architecture In A Granular Material Under Compression, Lia Papadopoulous, James G. Puckett, Karen E. Daniels, Danielle S. Bassett
Physics and Astronomy Faculty Publications
As a granular material is compressed, the particles and forces within the system arrange to form complex and heterogeneous collective structures. Force chains are a prime example of such structures, and are thought to constrain bulk properties such as mechanical stability and acoustic transmission. However, capturing and characterizing the evolving nature of the intrinsic inhomogeneity and mesoscale architecture of granular systems can be challenging. A growing body of work has shown that graph theoretic approaches may provide a useful foundation for tackling these problems. Here, we extend the current approaches by utilizing multilayer networks as a framework for directly quantifying …
Reconstructing Three-Dimensional Shape Envelopes From Time-Resolved Small-Angle X-Ray Scattering Data, Jessica Lamb, Lisa W. Kwok, Xiangyun Qiu, Kurt Andresen, Hye Yoon Park, Lois Pollack
Reconstructing Three-Dimensional Shape Envelopes From Time-Resolved Small-Angle X-Ray Scattering Data, Jessica Lamb, Lisa W. Kwok, Xiangyun Qiu, Kurt Andresen, Hye Yoon Park, Lois Pollack
Physics and Astronomy Faculty Publications
Modern computing power has made it possible to reconstruct low-resolution, three-dimensional shapes from solution small-angle X-ray scattering (SAXS) data on biomolecules without a priori knowledge of the structure. In conjunction with rapid mixing techniques, SAXS has been applied to time resolve conformational changes accompanying important biological processes, such as biomolecular folding. In response to the widespread interest in SAXS reconstructions, their value in conjunction with such time-resolved data has been examined. The group I intron from Tetrahymena thermophila and its P4–P6 subdomain are ideal model systems for investigation owing to extensive previous studies, including crystal structures. The goal of this …
Focusing Capillary Optics For Use In Solution Small-Angle X-Ray Scattering, Jessica S. Lamb, Sterling Cornaby, Kurt Andresen, Lisa W. Kwok, Hye Yoon Park, Xiangyun Qiu, Detlef-M. Smilgies, Donald H. Bilderback, Lois Pollack
Focusing Capillary Optics For Use In Solution Small-Angle X-Ray Scattering, Jessica S. Lamb, Sterling Cornaby, Kurt Andresen, Lisa W. Kwok, Hye Yoon Park, Xiangyun Qiu, Detlef-M. Smilgies, Donald H. Bilderback, Lois Pollack
Physics and Astronomy Faculty Publications
Measurements of the global conformation of macromolecules can be carried out using small-angle X-ray scattering (SAXS). Glass focusing capillaries, manufactured at the Cornell High Energy Synchrotron Source (CHESS), have been successfully employed for SAXS measurements on the heme protein cytochrome c. These capillaries provide high X-ray flux into a spot size of tens of micrometres, permitting short exposures of small-volume samples. Such a capability is ideal for use in conjunction with microfluidic mixers, where time resolution may be determined by beam size and sample volumes are kept small to facilitate mixing and conserve material.