Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 5 of 5
Full-Text Articles in Physics
Role Of Draw Rate And Molecular Weight When Electrospun Nanofibers Are Post-Drawn With Residual Solvent, Adriano Conte, Xiao Hu, Vincent Beachley
Role Of Draw Rate And Molecular Weight When Electrospun Nanofibers Are Post-Drawn With Residual Solvent, Adriano Conte, Xiao Hu, Vincent Beachley
Faculty Scholarship for the College of Science & Mathematics
The postdrawing process is poorly understood for polymer nanofibers due to the difficulty of manipulating nanofiber structures. Here, an angled track system facilitates postdrawing of individual nanofibers with control of parameters including molecular weight, draw rate, draw ratio, and solvent evaporation time. In this study, the effects of molecular weight, draw rate, and relative residual solvent content on final nanofiber properties are investigated. Molecular weight is first investigated to clarify any influence polymer chain length can have on drawing in facilitating or hindering chain extensibility. Polyacrylonitrile nanofibers with 50 and 150 kDa molecular weights behave similarly with postdrawing resulting in …
Multifunctional Silk Fibroin – Poly(L-Lactic Acid) Porous Nanofibers: Designing Adjustable Nanopores To Control Composite Properties And Biological Responses, Hangling Gu, Fang Wang, Hao Liu, Kyle Printon, Xiao Hu
Multifunctional Silk Fibroin – Poly(L-Lactic Acid) Porous Nanofibers: Designing Adjustable Nanopores To Control Composite Properties And Biological Responses, Hangling Gu, Fang Wang, Hao Liu, Kyle Printon, Xiao Hu
Faculty Scholarship for the College of Science & Mathematics
Nano-scale renewable porous materials have a wide range of applications in the biomedical field such as tissue engineering and biosensors due to their high biocompatibility and large surface area. In this study, a composite of silk fibroin and poly(L-lactic acid) was electrospun together to form a porous nanofiber biomaterial with 11 blending ratios to tune the porosity of the single fibers (19.3–49%). This is highly advantageous as porous fibers effectively promoted cell attachment and proliferation while also manipulating cell growth. The protein-polymer molecular interactions, structures and crystal contents, as well as the melting and glass transition behaviors of the composites …
Controlling The Structure And Properties Of Semi-Crystalline Cellulose/Silk-Fibroin Biocomposites By Ionic Liquid Type And Hydrogen Peroxide Concentration, Stacy A. Love, Xiao Hu, David Salas-De La Cruz
Controlling The Structure And Properties Of Semi-Crystalline Cellulose/Silk-Fibroin Biocomposites By Ionic Liquid Type And Hydrogen Peroxide Concentration, Stacy A. Love, Xiao Hu, David Salas-De La Cruz
Faculty Scholarship for the College of Science & Mathematics
This work reports how to tune the semi-crystallinity of a blended microcrystalline cellulose/silk-fibroin biocomposite using ionic liquids and various coagulation agents. The morphological and thermal properties of a blended 1:1 polymeric system are studied as a function of polymer fabrication parameters. Ionic liquids, 1-ethyl-3-methylimidazolium acetate verses 1-ethyl-3-methylimidazolium chloride, are used as competing solvent types and six hydrogen peroxide solutions (1—25%) plus water are used as varying coagulation agents. Analysis of the results demonstrate that solvent anion type, Ac− verses Cl−, affects protein secondary structure formation, and that solvent anion type and the concentration of hydrogen peroxide changes morphology and thermal …
Post-Acquisition Hyperpolarized 29silicon Mr Image Processing For Visualization Of Colorectal Lesions Using A User-Friendly Graphical Interface, Caitlin V Mccowan, Duncan Salmon, Jingzhe Hu, Shivanand Pudakalakatti, Nicholas Whiting, Jennifer S Davis, Daniel D Carson, Niki M Zacharias, Pratip K Bhattacharya, Mary C Farach-Carson
Post-Acquisition Hyperpolarized 29silicon Mr Image Processing For Visualization Of Colorectal Lesions Using A User-Friendly Graphical Interface, Caitlin V Mccowan, Duncan Salmon, Jingzhe Hu, Shivanand Pudakalakatti, Nicholas Whiting, Jennifer S Davis, Daniel D Carson, Niki M Zacharias, Pratip K Bhattacharya, Mary C Farach-Carson
Faculty Scholarship for the College of Science & Mathematics
Medical imaging devices often use automated processing that creates and displays a self-normalized image. When improperly executed, normalization can misrepresent information or result in an inaccurate analysis. In the case of diagnostic imaging, a false positive in the absence of disease, or a negative finding when disease is present, can produce a detrimental experience for the patient and diminish their health prospects and prognosis. In many clinical settings, a medical technical specialist is trained to operate an imaging device without sufficient background information or understanding of the fundamental theory and processes involved in image creation and signal processing. Here, we …
Recent Progress In Biopolymer-Based Hydrogel Materials For Biomedical Applications., Ayaz Mahmood, Dev Patel, Brandon Hickson, John Desrochers, Xiao Hu
Recent Progress In Biopolymer-Based Hydrogel Materials For Biomedical Applications., Ayaz Mahmood, Dev Patel, Brandon Hickson, John Desrochers, Xiao Hu
Faculty Scholarship for the College of Science & Mathematics
Hydrogels from biopolymers are readily synthesized, can possess various characteristics for different applications, and have been widely used in biomedicine to help with patient treatments and outcomes. Polysaccharides, polypeptides, and nucleic acids can be produced into hydrogels, each for unique purposes depending on their qualities. Examples of polypeptide hydrogels include collagen, gelatin, and elastin, and polysaccharide hydrogels include alginate, cellulose, and glycosaminoglycan. Many different theories have been formulated to research hydrogels, which include Flory-Rehner theory, Rubber Elasticity Theory, and the calculation of porosity and pore size. All these theories take into consideration enthalpy, entropy, and other thermodynamic variables so that …