Physics Commons^™

Study Of The Etaprimepi0 System In Gluex, Rupesh Dotel

FIU Electronic Theses and Dissertations

The η′π is an important decay channel for the potentially exotic hybrid meson π1(1600) that has been detected in the COMPASS, VES and E852 experiments. These previous experiments used a charged pion beam as a probe. In contrast, the GlueX experiment is designed to search for the exotic hybrid mesons using a linearly polarized photon beam. This thesis project analyzes the η′π0 system produced in GlueX by the reaction γp → η′π0p. After optimizing the event selection to minimize background contributions, a mass independent partial wave analysis is performed in search of an exotic signature. Within the currently available statistical …

The Role Of Conformational Changes In Viral And Bacterial Protein Functions, Md Lokman Hossen

FIU Electronic Theses and Dissertations

Proteins do versatile work in cells. They require a cascade of structural changes to perform different tasks like binding to the other neighboring biomolecules, transporting small chemicals, activating a chemical reaction, etc. The structural conformations of proteins can be critical in changing their working ability. In this dissertation, I investigated the role of conformational changes of viral protein, e.g., spike and envelope protein of SARS-CoV-2, and bacterial protein, e.g., multidrug transporter and toxic extrusion protein- PfMATE from Pyrococcus furiosus. Also, I performed molecular docking-based drug screening targeting the E protein to suggest a set of drugs that can be repurposed …

The Valence Quark Structure Of The Nucleon, Christopher A. Leon

FIU Electronic Theses and Dissertations

The nucleon is a composite object, formed from a sea of quarks, anti-quarks and gluons being continuously created and annihilated. Among this complexity, however, there are three valence quarks that give the nucleon its baryon and flavor numbers. Here we investigate the dynamical structure of valence quarks inside the nucleon. The primary tool used will be patron distribution functions (PDFs), which give the distribution of momentum fraction, x, of the quarks and gluons inside the nucleon. By examining the PDFs of the valence quarks from phenomenological fits, we derive a new model-independent relation of PDF peaks and connect it to …

Many-Body Effects In Atomic Ensembles Probed By Optical Two-Dimensional Coherent Spectroscopy, Danfu Liang

FIU Electronic Theses and Dissertations

Quantum information science provides humankind with post-Moore era technology and advanced principles and methods in the development of information science. Implementing practical quantum simulations through many-body quantum systems is a fundamental goal in quantum information science. Therefore, the demand for the achievement of quantum information processing devices inevitably requires the study of the many-body effect in the multi-atom system. Due to the transition-induced dipole moment, neutral atoms can interact without a permanent dipole moment. The interaction plays an essential role in many-body effects, such as energy shifts and changes in dephasing rates. In addition, its long-range nature has confirmed the …

In Silico Identification Of Vaccine Candidates Against Viral Infections, Prabin Baral

FIU Electronic Theses and Dissertations

There are many viral diseases without effective treatments or vaccines. These viruses can cause catastrophic epidemics such as the Lassa, Ebola, and Marburg viruses. Similarly, the recent coronavirus pandemic is of great concern as new variants are continuously emerging with decreased susceptibility to antibodies and vaccines that were developed for earlier strains. A critical step in the immune system’s fight against viruses involves an immunological protein molecule binding to a viral protein molecule. I investigate the atomic and molecular details of binding site recognition and binding interactions and dynamics for three important viruses.

Antigens are molecules, such as viral proteins, …