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Theoretical Proposal For A Biosensing Approach Based On A Linear Array Of Immobilized Gold Nanoparticles, S.M.H. Rafsanjani, T. Cheng, S. Mittler, Chitra Rangan

Physics Publications

We propose a sensing mechanism for detection of analytes that can specifically recognized. The sensor is based on closely-spaced chains of functionalized gold nanoparticles (NPs) immobilized on a waveguide surface, with the signal detected by evanescent waveguide absorption spectroscopy. The localized surface plasmon spectrum of a linear array of closely-spaced, hemispherical gold NPs is calculated using the discrete dipole approximation. The plasmon band is found to broaden to a nanowirelike spectrum when a dielectric coating is put on the particles, and the light polarization is along the NP chain. The origin of this broadening is shown to be the polarization-dependent …