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Some Comments On The Concepts Of Dose And Dose Equivalent, Robert Katz, Werner Hofmann

Robert Katz Publications

Although dose is the simplest and most widely used measurement of a radiation field, it does not always lead to an unambiguous estimate of response. This is reflected in the very wide range of relative biologic effectiveness (RBE) values for biological systems. The ambiguity arises from the focus on energy deposition as the source of biological effect, whether in macroscopic or microscopic volumes. The properties of the biological detector play a role equally important to the properties of the radiation field in their interaction. To predict even the most experimentally accessible biological response, cell killing, we must know the probability …