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Full-Text Articles in Physics
Investigation Of Flow Disturbances And Multi-Directional Wall Shear Stress In The Stenosed Carotid Artery Bifurcation Using Particle Image Velocimetry, Amanda L. Dicarlo
Investigation Of Flow Disturbances And Multi-Directional Wall Shear Stress In The Stenosed Carotid Artery Bifurcation Using Particle Image Velocimetry, Amanda L. Dicarlo
Electronic Thesis and Dissertation Repository
Hemodynamics and shear forces are associated with pathological changes in the vascular wall and its function, resulting in the focal development of atherosclerosis. Flow complexities that develop in the presence of established plaques create environments favourable to thrombosis formation and potentially plaque rupture leading to stroke. The carotid artery bifurcation is a common site of atherosclerosis development. Recently, the multi-directional nature of shear stress acting on the endothelial layer has been highlighted as a risk factor for atherogenesis, emphasizing the need for accurate measurements of shear stress magnitude as well direction. In the absence of comprehensive patient specific datasets numerical …
Experimental Measurements Of Human Cough Airflows From Healthy Subjects And Those Infected With Respiratory Viruses, Nicholas Dudalski
Experimental Measurements Of Human Cough Airflows From Healthy Subjects And Those Infected With Respiratory Viruses, Nicholas Dudalski
Electronic Thesis and Dissertation Repository
Research concerning person-to-person respiratory virus transmission is required to develop reliable, evidence-based infection prevention and control measures. Experimental studies of human coughs were comprehensively critiqued from the point of view of methodologies, aerodynamics, droplet dispersion and virology. Particle image velocimetry (PIV) and hot-wire anemometry (HWA) measurements were conducted at x=1 m away from the mouth of human subjects to develop a model for cough flow behaviour at greater distances from the mouth than those studied previously. Experiments were conducted for sick subjects who had presented with influenza-like illness, together with a cohort of healthy subjects. Biological aerosol sampling was conducted …
Piv-Based Investigation Of Hemodynamic Factors In Diseased Carotid Artery Bifurcations With Varying Plaque Geometries, Sarah Kefayati
Piv-Based Investigation Of Hemodynamic Factors In Diseased Carotid Artery Bifurcations With Varying Plaque Geometries, Sarah Kefayati
Electronic Thesis and Dissertation Repository
Ischemic stroke is often a consequence of complications due to clot formation (i.e. thrombosis) at the site of an atherosclerotic plaque developed in the internal carotid artery. Hemodynamic factors, such as shear-stress forces and flow disturbances, can facilitate the key mechanisms of thrombosis. Atherosclerotic plaques can differ in the severity of stenosis (narrowing), in eccentricity (symmetry), as well as inclusion of ulceration (wall roughness). Therefore, in terms of clinical significance, it is important to investigate how the local hemodynamics of the carotid artery is mediated by the geometry of plaque. Knowledge of thrombosis-associated hemodynamics may provide a basis to introduce …