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Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul
Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul
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Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …
Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul
Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul
Browse all Theses and Dissertations
Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …
Evanescent Microwave Microscopy Of Porcine Skin Tissue, Richard A. Kleismit
Evanescent Microwave Microscopy Of Porcine Skin Tissue, Richard A. Kleismit
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This thesis describes the application of a custom designed λ/4 resonant coaxial probe to measurements of the complex permittivity of in vitro freshly excised porcine skin tissue. The dielectric properties of the organic material within the near field of the tip of the probe frustrates the electric field and measurably changes the resonant frequency and quality factor Q of the coaxial sensor, where the change in resonant frequency and quality factor of a tuned resonance is measured as a function of tip-sample separation. The design of the probe enables better spatial resolution than previously developed probes. The following studies were …