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Full-Text Articles in Physics

Investigation On The Rons And Bactericidal Effects Induced By He + O2 Cold Plasma Jets: In Open Air And In An Airtight Chamber, Han Xu, Dingxin Liu, Weitao Wang, Zhijie Liu, Li Guo, Mingzhe Rong, Michael G. Kong Nov 2018

Investigation On The Rons And Bactericidal Effects Induced By He + O2 Cold Plasma Jets: In Open Air And In An Airtight Chamber, Han Xu, Dingxin Liu, Weitao Wang, Zhijie Liu, Li Guo, Mingzhe Rong, Michael G. Kong

Bioelectrics Publications

He + O2 plasma jets in open air and in an airtight chamber are comparatively studied, with respect to their production of gaseous/aqueous reactive species and their antibacterial effects. Under the same discharge power, the plasma jet in open air has higher densities of gaseous reactive species and a higher concentration of aqueous H2O2 but lower concentrations of aqueous OH and O2-. In addition, the increase in the O2 ratio in He in both plasma jets causes a linear decrease in the population of gaseous reactive species, except for O(3p5P) …


No2- And No3- Enhance Cold Atmospheric Plasma Induced Cancer Cell Death By Generation Of Onoo-, Dehui Xu, Qingjie Cui, Yujing Xu, Zhijie Liu, Zeyu Chen, Wenjie Xia, Hao Zhang, Dingxin Liu, Hailan Chen, Michael G. Kong Oct 2018

No2- And No3- Enhance Cold Atmospheric Plasma Induced Cancer Cell Death By Generation Of Onoo-, Dehui Xu, Qingjie Cui, Yujing Xu, Zhijie Liu, Zeyu Chen, Wenjie Xia, Hao Zhang, Dingxin Liu, Hailan Chen, Michael G. Kong

Bioelectrics Publications

Cold atmospheric plasma (CAP) is a rapidly developed technology that has been widely applied in biomedicine especially in cancer treatment. Due to the generation of various active species in plasma, CAP could induce various tumor cells death and showed a promising potential in cancer therapy. To enhance the biological effects of gas plasma, changing the discharging parameters is the most commonly used method, yet increasing discharging power will lead to a higher possibility of simultaneously damage surrounding tissues. In this study, by adding nontoxic concentration of additional nitrite and nitrate in the medium, we found that anti-tumor effect of CAP …


Inactivation Of Myeloma Cancer Cells By Helium And Argon Plasma Jets: The Effect Comparison And The Key Reactive Species, Zeyu Chen, Qingjie Cui, Chen Chen, Dehui Xu, Dingxin Liu, H. L. Chen, Michael G. Kong Feb 2018

Inactivation Of Myeloma Cancer Cells By Helium And Argon Plasma Jets: The Effect Comparison And The Key Reactive Species, Zeyu Chen, Qingjie Cui, Chen Chen, Dehui Xu, Dingxin Liu, H. L. Chen, Michael G. Kong

Bioelectrics Publications

In plasma cancer therapy, the inactivation of cancer cells under plasma treatment is closely related to the reactive oxygen and nitrogen species (RONS) induced by plasmas. Quantitative study on the plasma-induced RONS that related to cancer cells apoptosis is critical for advancing the research of plasma cancer therapy. In this paper, the effects of several reactive species on the inactivation of LP-1 myeloma cancer cells are comparatively studied with variable working gas composition, surrounding gas composition, and discharge power. The results show that helium plasma jet has a higher cell inactivation efficiency than argon plasma jet under the same discharge …


Production And Correlation Of Reactive Oxygen And Nitrogen Species In Gas- And Liquid-Phase Generated By Helium Plasma Jets Under Different Pulse Widths, Zhijie Liu, Chunxi Zhou, Dingxin Liu, Dehui Xu, Wenjie Xia, Qingjie Cui, Bingchuan Wang, Michael G. Kong Jan 2018

Production And Correlation Of Reactive Oxygen And Nitrogen Species In Gas- And Liquid-Phase Generated By Helium Plasma Jets Under Different Pulse Widths, Zhijie Liu, Chunxi Zhou, Dingxin Liu, Dehui Xu, Wenjie Xia, Qingjie Cui, Bingchuan Wang, Michael G. Kong

Bioelectrics Publications

In this paper, we present the effects of the pulse width (PW) on the plasma jet's discharge characteristics, particularly focusing on the production and correlation of the reactive oxygen and nitrogen species (RONS) in gas- and liquid-phase. It is found that the length of plasma jet plume first increases before the PW of 10 μs, then gradually decreases and finally almost remains unchanged beyond 150 μs. The plasma bullet disappears after the falling edge of the voltage pulse at low PW, while it terminates far ahead of the falling edge of voltage pulse at high PW. This is …


Comparison Between The Water Activation Effects By Pulsed And Sinusoidal Helium Plasma Jets, Han Xu, Dingxin Liu, Wenjie Xia, Chen Chen, Weitao Wang, Zhijie Liu, Xiaohua Wang, Michael G. Kong Jan 2018

Comparison Between The Water Activation Effects By Pulsed And Sinusoidal Helium Plasma Jets, Han Xu, Dingxin Liu, Wenjie Xia, Chen Chen, Weitao Wang, Zhijie Liu, Xiaohua Wang, Michael G. Kong

Bioelectrics Publications

Comparisons between pulsed and sinusoidal plasma jets have been extensively reported for the discharge characteristics and gaseous reactive species, but rarely for the aqueous reactive species in water solutions treated by the two types of plasma jets. This motivates us to compare the concentrations of aqueous reactive species induced by a pulsed and a sinusoidal plasma jet, since it is widely reported that these aqueous reactive species play a crucial role in various plasma biomedical applications. Experimental results show that the aqueous H2O2, OH/O2, and O2/ONOO induced by the …