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Wright State University

2017

Cell culture

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Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul Jan 2017

Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul

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Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …


Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul Jan 2017

Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul

Browse all Theses and Dissertations

Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …