Physics Commons^™

The Potential Of Vibrational Spectroscopy In The Early Detection Of Cervical Cancer: An Exciting Emerging Field, Eoghan O'Faolain, Mary Hunter, Joe Byrne, Peter Kelehan, Hugh Byrne, Fiona Lyng

Conference papers

The application of vibrational spectroscopy to disease diagnosis is a relatively new, rapidly evolving scientific field. Techniques such as Raman and infrared spectroscopy have shown great promise in this regard over the past number of years. This study directly compared Raman spectroscopy and synchrotron infrared (SR-IR) spectroscopy on parallel cervical cancer samples. Both frozen and dewaxed formalin fixed paraffin preserved tissue sections were examined. Both tissue types produced good quality Raman and SR-IR spectra, although the lesser processed, frozen tissue sections displayed the most detailed spectra. Spectroscopy was shown capable of discriminating between different cell types in normal cervical tissue. …