Physics Commons^™

Investigation Of Membrane Protein Dynamics Using Correlative Single-Particle Tracking And Super-Resolution Microscopy Combined With Bayesian Inference Of Diusion In Arbitrary Landscapes, Hanieh Mazloom Farsibaf

Physics & Astronomy ETDs

Many experiments have shown that the diffusive motion of lipids and membrane proteins are slower on the cell surface than those in artificial lipid bilayers or blebs. One hypothesis that may partially explain this mystery is the effect of the cytoskeleton structures on the protein dynamics. To test this hypothesis, we designed a high-speed single particle tracking microscope and use a hybrid tracking and super-resolution approach on the same cell. We labeled the high-affinity FceRI receptor as a transmembrane protein and GPI-anchored proteins as an example of outer leaflet protein in Rat Basophilic Leukemia (RBL) cells and tracked these membrane …

Direct Observation Of Atomic Exchange During Surface Self-Diffusion, Matthew Aaron Koppa

Physics & Astronomy ETDs

The diffusion of adatoms across the (100) plane of iridium has been previously inferred to occur by an exchange mechanism based on site mapping. This study provides the first direct observation that surface self-diffusion can occur by exchange. Iridium enriched to ≥93% ¹⁹¹Ir was deposited onto an atomically clean and smooth Ir(100) plane as observed in an atom probe field ion microscope. Following thermally activated surface self-diffusion the adatom was field desorbed and mass analyzed. Observation of the ¹⁹³Ir isotope in one-half of the cases demonstrates conclusively that atomic exchange can occur during surface self-diffusion.

Dark Matter Production Beyond The Thermal Wimp Paradigm: An Exploration Of Early Matter Domination Scenarios, Jacek Ksawery Osinski

Physics & Astronomy ETDs

In the standard thermal history of the Universe, the energy density is dominated by radiation throughout the postinflationary era, until matter-radiation equality after big bang nucleosynthesis (BBN). However, we currently do not have any observational probes of the pre-BBN period, and radiation domination (RD) is therefore an assumption. Generic early Universe models predict the presence of additional components in the postinflationary Universe which can lead to periods of nonstandard evolution before the onset of BBN. A prominent example of such a period is a phase of early matter domination (EMD) in which the Universe undergoes matter-dominated expansion for a time, …

Using Natural Phenomena To Study The Ionosphere, Joseph Benjamin Malins

Physics & Astronomy ETDs

This dissertation explores novel techniques for observing the ionosphere using natural signals. The ionosphere is a region of plasma hundreds of kilometers above the Earth that affects communication and remote sensing applications across the world. Traditional techniques for observing the ionosphere involve using man made radio signals, either to reflect the signal at HF frequencies or to pass several signals through the ionosphere and compare the difference the ionosphere makes in the signals. However, such techniques are limited by the ability of equipment to produce these signals and by the numerous laws and regulations governing transmission of signals in the …

Electromagnetic Analysis Of Bidirectional Reflectance From Roughened Surfaces And Applications To Surface Shape Recovery, Julian Antolin Camarena

Physics & Astronomy ETDs

Scattering from randomly rough surfaces is a well-established sub area of electrodynamics. There remains much to be done since each surface and optical processes that may occur in within the scattering medium, and countless other scenarios, is different. There are also illumination models that describe lighting in a scene on the macroscopic scale where geometrical optics can be considered adequate. Of particular interest for us is the intersection of the physical scattering theories and the illumination models. We present two contributions: 1) A minimum of two independent images are needed since any opaque surface can be uniquely specified in terms …

The Production Cross Section Of The J/Ψ Meson Measured Using The Phenix Detector At √ S =510 Gev, Katherine Marie Deblasio

Physics & Astronomy ETDs

The inclusive differential production cross section of the J/ψ meson is measured with the PHENIX detector for p + p collisions at √ s = 510 GeV using the 2013 RHIC dataset. The measurement is performed using the dimuon decay channel at forward and backward rapidity ranges of 1.2 < |y| < 2.2 and for transverse momenta up to 12 GeV/c. The experimental results are compared to current predictions in NRQCD and serves to shed light on the ambiguity of the J/ψ production mechanism. The 2013 RHIC dataset provides unique challenges to the cross section measurement due to the effects of detector pile-up from multiple collisions. Techniques to quantify these effects are discussed.

Quantum Algorithms With Applications To Simulating Physical Systems, Anirban Ch Narayan Chowdhury

Physics & Astronomy ETDs

The simulation of quantum physical systems is expected to be an important application for quantum computers. The work presented in this dissertation aims to improve the resource requirements of quantum computers for solving simulation problems, by providing both novel quantum algorithms and improved implementations of existing ones. I present three main results that cover diverse aspects of simulation including equilibrium physics, the preparation of useful quantum states, and simulations based on classical stochastic processes. The results rely on established quantum algorithms and other recent techniques which I review. My first original contribution is a new quantum algorithm to sample from …

Studying The Properties Of Sf6 Gas Mixtures For Directional Dark Matter Detection, Randy J. Lafler

Physics & Astronomy ETDs

Although dark matter comprises approximately 85\% of the matter content of the universe, direct detection of dark matter remains elusive. As the available parameter space for dark matter candidates is pushed to lower and lower limits, the demand for larger, more sensitive detectors continues to grow. Although upscaling the detector improves the sensitivity, it greatly increases the cost and complexity of the experiment. Even after a dark matter signal is detected, there remains the possibility that an unknown background mimics the dark matter signal. Consequently, verifying the dark matter origin of a detection signal is an issue for any dark …

Searching For Supermassive Binary Black Holes And Their Gravitational Waves, Karishma Bansal

Physics & Astronomy ETDs

The recent discovery of gravitational waves (GWs) by the LIGO collaboration has opened a new observing window on the universe, but it is limited to the GWs in the frequency range of 10-1000 Hz. The main motivation of this thesis is to consider the possibility of detecting low frequency (nHz) GWs. In the pursuit of these waves, we need to understand their source of origin and build a detector with the required sensitivity. Low-frequency waves are expected as a result of coalescing binary supermassive black holes (SMBBHs). We hope to detect these waves in the near future using pulsar timing …

Circumstellar Sio Masers In The Bulge Asymmetries And Dynamical Evolution Survey, Michael Cullen Stroh

Physics & Astronomy ETDs

The Bulge Asymmetries and Dynamical Evolution (BAaDE) project aims to explore the complex structure of the inner Galaxy and Galactic Bulge, by using the 43 GHz receivers at the Karl G. Jansky Very Large Array (VLA) and the 86 GHz receivers at the Atacama Large Millimeter/submillimeter Array (ALMA) to observe SiO maser lines in red giant stars. The SiO maser transitions occur at radio frequencies, where extinction is negligible, thus allowing a dense sampling of line-of-sight velocities in the most crowded regions of the Milky Way.

The overall goal of this thesis is to characterize the SiO masers in the …

Topics In Three-Dimensional Imaging, Source Localization And Super-Resolution, Zhixian Yu

Physics & Astronomy ETDs

The realization that twisted light beams with helical phasefronts could carry orbital angular momentum (OAM) that is in excess of the photon's spin angular momentum (SAM) has spawned various important applications. One example is the design of novel imaging systems that achieve three-dimensional (3D) imaging in a single snapshot via the rotation of point spread function (PSF).

Based on a scalar-field analysis, a particular simple version of rotating PSF imagery, which was proposed by my advisor Dr. Prasad, furnishes a practical approach to perform 3D source localization using a spiral phase mask that generates a combination of Bessel vortex beams. …

Studies On The Generation And Detection Of Orbital Angular Momentum Based On Beam-Shaping Techniques, Xijie Luo

Physics & Astronomy ETDs

Light carrying orbital angular momentum (OAM) has many applications ranging from optical manipulation, imaging and remote sensing, and optical communications, and can be used to perform fundamental studies in quantum mechanics and quantum information. Moreover, single photons with high-order OAM allow for increasing the amount of information carried per photon in quantum communication. This thesis describes the study of methods for the preparation and detection of OAM of light in high mode order by utilizing beam shaping techniques using spatial light modulators (SLMs). The quality of the generated high-order OAM mode is limited by optical aberrations which are induced by …

Improving The Readout Of Semiconducting Qubits, Matthew Jon Curry

Physics & Astronomy ETDs

Semiconducting qubits are a promising platform for quantum computers. In particular, silicon spin qubits have made a number of advancements recently including long coherence times, high-fidelity single-qubit gates, two-qubit gates, and high-fidelity readout. However, all operations likely require improvement in fidelity and speed, if possible, to realize a quantum computer.

Readout fidelity and speed, in general, are limited by circuit challenges centered on extracting low signal from a device in a dilution refrigerator connected to room temperature amplifiers by long coaxial cables with relatively high capacitance. Readout fidelity specifically is limited by the time it takes to reliably distinguish qubit …

Compact Optical Frequency Standards For Future Applications Beyond The Laboratory, Kyle Martin

Physics & Astronomy ETDs

Atomic clocks provide one of the fundamental building blocks upon which modern telecommunications systems are constructed. Since the invention of the frequency comb in the early 2000s, laboratory frequency standards have quickly outpaced their compact counterparts. Compact clocks, however, have continued to leverage microwave transitions not yet exploring the advantages of an optical atomic clock. With the recent development of robust frequency combs compact optical clocks can now be realized. In this dissertation two atomic species are investigated for a compact atomic frequency standards. Both of these clocks are in different development stages but offer unique advantages. The optical rubidium …