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Full-Text Articles in Physics

Microfluidic Experiments Reveal That Antifreeze Proteins Bound To Ice Crystals Suffice To Prevent Their Growth, Yeliz Celik, Ran Drori, Natalya Pertaya-Braun, Aysun Altan, Tyler Barton, Maya Bar-Dolev, Alex Groisman, Peter L. Davies, Ido Braslavsky Dec 2012

Microfluidic Experiments Reveal That Antifreeze Proteins Bound To Ice Crystals Suffice To Prevent Their Growth, Yeliz Celik, Ran Drori, Natalya Pertaya-Braun, Aysun Altan, Tyler Barton, Maya Bar-Dolev, Alex Groisman, Peter L. Davies, Ido Braslavsky

Physics Faculty Research

Antifreeze proteins (AFPs) are a subset of ice-binding proteins that control ice crystal growth. They have potential for the cryopreservation of cells, tissues, and organs, as well as for production and storage of food and protection of crops from frost. However, the detailed mechanism of action of AFPs is still unclear. Specifically, there is controversy regarding reversibility of binding of AFPs to crystal surfaces. The experimentally observed dependence of activity of AFPs on their concentration in solution appears to indicate that the binding is reversible. Here, by a series of experiments in temperature-controlled microfluidic devices, where the medium surrounding ice …


Influence Of Line Tension On Spherical Colloidal Particles At Liquid-Vapor Interfaces, Sean P. Mcbride, Bruce M. Law Nov 2012

Influence Of Line Tension On Spherical Colloidal Particles At Liquid-Vapor Interfaces, Sean P. Mcbride, Bruce M. Law

Physics Faculty Research

Atomic force microscopy (AFM) imaging of isolated submicron dodecyltrichlorosilane coated silica spheres, immobilized at the liquid polystyrene- (PS-) air interface at the PS glass transition temperature, Tg , allows for determination of the contact angle θ versus particle radius R . At Tg , all θ versus R measurements are well described by the modified Young’s equation for a line tension τ=0.93  nN . The AFM measurements are also consistent with a minimum contact angle θmin and minimum radius Rmin , below which single isolated silica spheres cannot exist at the PS-air interface.


Progress On: “Coherent Terahertz Acoustic Phonon Scattering: Novel Diagnostic For Erosion In Plasma Thruster Discharge Chamber Walls", Thomas E. Wilson, Iain D. Boyd Sep 2012

Progress On: “Coherent Terahertz Acoustic Phonon Scattering: Novel Diagnostic For Erosion In Plasma Thruster Discharge Chamber Walls", Thomas E. Wilson, Iain D. Boyd

Physics Faculty Research

The study is based on the success in obtaining the first experimental evidence for the direct excitation of coherent nanosecond-pulsed high-frequency acoustic phonons in semiconducting doping superstructures by electromagnetic fields of the same frequency. Acoustic phonons are detected by a superconducting bolometer, with nanosecond resolution, at the appropriate time-of-flight across a (100) silicon substrate for ballistic longitudinal phonons when a silicon delta-doped doping superlattice is illuminated with grating-coupled nanosecond-pulsed 246-GHz laser radiation with an approximate power density of 1 kW/mm2. The absorbed phonon power density in the bolometer detector is estimated to be 10 μW/mm2, in …


Long Reach Cantilevers For Sub-Cellular Force Measurements, Govind Paneru, Prem S. Thapa, Sean P. Mcbride Aug 2012

Long Reach Cantilevers For Sub-Cellular Force Measurements, Govind Paneru, Prem S. Thapa, Sean P. Mcbride

Physics Faculty Research

Maneuverable, high aspect ratio poly 3-4 ethylene dioxythiophene (PEDOT) fibers are fabricated for use as cellular force probes that can interface with individual pseudopod adhesive contact sites without forming unintentional secondary contacts to the cell. The straight fibers have lengths between 5 and 40 μm and spring constants in the 0.07-23.2 nN μm-1 range. The spring constants of these fibers were measured directly using an atomic force microscope (AFM). These AFM measurements corroborate determinations based on the transverse vibrational resonance frequencies of the fibers, which is a more convenient method. These fibers are employed to characterize the time …


New Insights Into Ice Growth And Melting Modifications By Antifreeze Proteins, Maya Bar-Dolev, Yeliz Celik, J. S. Wettlaufer, Peter L. Davies, Ido Braslavsky Jun 2012

New Insights Into Ice Growth And Melting Modifications By Antifreeze Proteins, Maya Bar-Dolev, Yeliz Celik, J. S. Wettlaufer, Peter L. Davies, Ido Braslavsky

Physics Faculty Research

Antifreeze proteins (AFPs) evolved in many organisms, allowing them to survive in cold climates by controlling ice crystal growth. The specific interactions of AFPs with ice determine their potential applications in agriculture, food preservation and medicine. AFPs control the shapes of ice crystals in a manner characteristic of the particular AFP type. Moderately active AFPs cause the formation of elongated bipyramidal crystals, often with seemingly defined facets, while hyperactive AFPs produce more varied crystal shapes. These different morphologies are generally considered to be growth shapes. In a series of bright light and fluorescent microscopy observations of ice crystals in solutions …


Testing A Model For The Well-Posedness Of The Cauchy-Characteristic Problem In Bondi Coordinates, Maria Babiuc-Hamilton, Jeff Winicour Apr 2012

Testing A Model For The Well-Posedness Of The Cauchy-Characteristic Problem In Bondi Coordinates, Maria Babiuc-Hamilton, Jeff Winicour

Physics Faculty Research

Gravity waves reveal colliding black holes, galaxies, the birth of a black hole in a supernova and the growth pains of our universe. Gravitational waves are unambiguous measured only at future null infinity.


Using Radial Basis Functions To Interpolate Along Single-Null Characteristics, Maria Babiuc-Hamilton, Clyde E. Meador Apr 2012

Using Radial Basis Functions To Interpolate Along Single-Null Characteristics, Maria Babiuc-Hamilton, Clyde E. Meador

Physics Faculty Research

The Cauchy-Characteristic Extraction (CCE) technique is the most precise method available for the computation of the gravitational waves obtained from numerical simulations of binary black hole mergers. This technique utilizes the characteristic evolution to extend the simulation to null infinity, where the waveform is computed in inertial coordinates. Although we recently made CCE publicly available to the numerical relativity community, there is still room for improvement, and the most important is enhancing the overall accuracy of the code, by upgrading the numerical methods used for interpolation and differentiation. One of the most promising ways is to use the Radial Basis …


Modeling The Influence Of Antifreeze Proteins On Three-Dimensional Ice Crystal Melt Shapes Using A Geometric Approach, Jun Jie Liu, Yangzong Qin, Maya Bar Dolev, Yeliz Celik, J. S. Wettlaufer, Ido Braslavsky Jan 2012

Modeling The Influence Of Antifreeze Proteins On Three-Dimensional Ice Crystal Melt Shapes Using A Geometric Approach, Jun Jie Liu, Yangzong Qin, Maya Bar Dolev, Yeliz Celik, J. S. Wettlaufer, Ido Braslavsky

Physics Faculty Research

The melting of pure axisymmetric ice crystals has been described previously by us within the framework of so-called geometric crystal growth. Nonequilibrium ice crystal shapes evolving in the presence of hyperactive antifreeze proteins (hypAFPs) are experimentally observed to assume ellipsoidal geometries (“lemon” or “rice” shapes). To analyze such shapes we harness the underlying symmetry of hexagonal ice Ih and extend two-dimensional geometric models to three-dimensions to reproduce the experimental dissolution process. The geometrical model developed will be useful as a quantitative test of the mechanisms of interaction between hypAFPs and ice.