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Full-Text Articles in Physics

Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal Nov 2022

Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal

Department of Paediatrics and Child Health

Numerous safe and effective coronavirus disease 2019 vaccines have been developed worldwide that use various delivery technologies and engineering strategies. We show here that vaccines containing prefusion-stabilizing S mutations elicit antibody responses in humans with enhanced recognition of S and the S1 subunit relative to postfusion S as compared with vaccines lacking these mutations or natural infection. Prefusion S and S1 antibody binding titers positively and equivalently correlated with neutralizing activity, and depletion of S1-directed antibodies completely abrogated plasma neutralizing activity. We show that neutralizing activity is almost entirely directed to the S1 subunit and that variant cross-neutralization is mediated …


Ultrashort Pulse Laser Filamentation Electrical And Optical Diagnostic Comparison, James E. Wymer Aug 2022

Ultrashort Pulse Laser Filamentation Electrical And Optical Diagnostic Comparison, James E. Wymer

Optical Science and Engineering ETDs

Results presented here examine the effect of changing gas pressure on the radio frequency (RF) emissions of an ultrashort pulse laser filament plasma and how those emissions vary longitudinally in the laser focal region. We use a WR284 rectangular waveguide with a 1.5 cm hole that allows the beam through. A 3.2 GHz microwave signal is emitted in the waveguide, and signals are received through a waveguide-to-coax antenna connected to an HP8470B Schottky diode. By enabling and disabling the 3.2 GHz signal, we measure both the self-emitted RF from a USPL filament and subsequently the degree of attenuation a filament …


Electrothermal Plenum Thruster Simulations Varying Input Pressure And Voltage, Naomi Nicole Ingram May 2022

Electrothermal Plenum Thruster Simulations Varying Input Pressure And Voltage, Naomi Nicole Ingram

Open Access Theses & Dissertations

A radiofrequency electrothermal thruster is designed and simulated to create a low ionization energy plasma from a neutral propellant using a radio-frequency power. With an asymmetrical surface area ratio between the grounded and powered electrode, ion-neutral charge exchange collisions occurring within the propellant result in propellant heating. The Electrothermal Plenum Thruster conducts this propellant heating in an annular plenum chamber in attempt to maximize propellant heating. A software called CFD-ACE+ is utilized to demonstrate the effects of an enhanced sheath from the asymmetrical power coupling arrangement. Two sets of simulations are run to understand how input variables affect the plasma …


Whistler Waves: Modeling And Observations, Daniel Williams Apr 2022

Whistler Waves: Modeling And Observations, Daniel Williams

Doctoral Dissertations and Master's Theses

The thesis presents the results of all the research from the published and in publication process research in the Journal of Geophysical Research [1]. This research focuses on whistler wave ducting events in the equatorial magnetosphere. High-density ducts are the main focus of whistler study in both studies as they are commonly observed by the Van Allen Probe satellites. A three-step procedure based on the analysis of the whistler wave dispersion relation and numerical simulations of the electron magnetohydrodynamics model. We use this model to identify the parallel and perpendicular wave numbers of the “most trapped” wave in an attempt …