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Full-Text Articles in Physics
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
Dissertations and Theses
Motility of microorganisms is understudied but provides useful insights into their behavior. Organisms' ability to move autonomously changes how they interact with their environment--finding nutrients, interacting with other organisms, and avoiding unfavorable conditions. Understanding motility features can also be used to identify specific species, such as the identification of Vibrio cholerae in human samples. Motility might also be used as evidence of life existing in even the most extreme environments on Earth, and possibly beyond. Specialized microscopy systems can be required to examine the motility of microorganisms due to the nature of the environments to which the instruments are exposed. …
A Novel Phase And Spectroscopic Imaging Technique To Evaluate Cellular Functions, Ting Chean Khoo
A Novel Phase And Spectroscopic Imaging Technique To Evaluate Cellular Functions, Ting Chean Khoo
Legacy Theses & Dissertations (2009 - 2024)
This thesis presents the application of Raman spectroscopy, digital holographic microscope (DHM) and transport intensity equation (TIE) in imaging biological samples. Raman spectroscopy is a non-destructive technique that can provide chemical structure, concentration, temperature, and molecular interactions. On the other hand, DHM and TIE provide physical measurements such as height, width, area and volume.We applied Raman spectroscopy to study iron-bound transferrin (Tf) in intact human breast cancer cells. Iron is an essential element required for human life and is highly regulated in the body. As the exact mechanisms of iron-bound Tf in cells are not well known, we developed a …