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Full-Text Articles in Physics

Computational Methods For Propagation Of Optical Fields With The Angle-Impact Wigner Function, Jeremy Wittkopp Aug 2022

Computational Methods For Propagation Of Optical Fields With The Angle-Impact Wigner Function, Jeremy Wittkopp

Legacy Theses & Dissertations (2009 - 2024)

In designing an optical setup for an experiment, one usually turns to simulations first in order to model the propagation of light through the proposed system. This way, the experimenter can determine if the system is operating as intended. In order for these simulations to be useful, they need to properly describe the propagation of light. In order to simplify calculations, most contemporary software makes assumptions on the nature of the light being propagated. Specifically, simulations typically consider optical fields that are beam-like (i.e., most of the rays comprising the field deviate only slightly in angle from the beam's primary …


A Novel Phase And Spectroscopic Imaging Technique To Evaluate Cellular Functions, Ting Chean Khoo Jan 2022

A Novel Phase And Spectroscopic Imaging Technique To Evaluate Cellular Functions, Ting Chean Khoo

Legacy Theses & Dissertations (2009 - 2024)

This thesis presents the application of Raman spectroscopy, digital holographic microscope (DHM) and transport intensity equation (TIE) in imaging biological samples. Raman spectroscopy is a non-destructive technique that can provide chemical structure, concentration, temperature, and molecular interactions. On the other hand, DHM and TIE provide physical measurements such as height, width, area and volume.We applied Raman spectroscopy to study iron-bound transferrin (Tf) in intact human breast cancer cells. Iron is an essential element required for human life and is highly regulated in the body. As the exact mechanisms of iron-bound Tf in cells are not well known, we developed a …


System Measurements For X-Ray Phase And Diffraction Imaging, Erik Wolfgang Tripi Jan 2022

System Measurements For X-Ray Phase And Diffraction Imaging, Erik Wolfgang Tripi

Legacy Theses & Dissertations (2009 - 2024)

In medical imaging, X rays are used to look inside the body to find fractures in bones, abnormal masses, cavities in teeth, and so on. What makes X rays so good at looking at these types of structures is the X ray’s penetration power. When imaging soft tissue to search for tumors, X-ray images tend to have difficulty performing well. The reason for this is that the background structures, such as fat or fibro glandular tissue have similar absorption coefficients as the tumor. Mammography tends to have a high false positive rate and can miss tumors entirely as well. There …