Open Access. Powered by Scholars. Published by Universities.®
- Publication
- Publication Type
Articles 1 - 5 of 5
Full-Text Articles in Physics
Development Of A Low Field Mri-Based Approach For Observation Of Water Penetration Into Clay: Preliminary Results, Shivam Gupta
Development Of A Low Field Mri-Based Approach For Observation Of Water Penetration Into Clay: Preliminary Results, Shivam Gupta
Undergraduate Student Research Internships Conference
Magnetic resonance imaging (MRI) are considered one of the most efficient and non-invasive methods of observing water content in permeable substances. MRI can visualize and quantify the movement of water in real time. In this study, MRI was used to observe the water penetration through clay. Furthermore, MRI can acquire three-dimensional data due to its radio-frequency signals from any orientation. The contrast of the images produced by MRI is a display of the fluid concentration. As such, any change in the contrast intensity is interpreted as a regional change in the concentration of fluid. This report summarizes the preliminary results …
Simulating 129-Xe Hyperpolarization, Jacob F. Abiad
Simulating 129-Xe Hyperpolarization, Jacob F. Abiad
Undergraduate Student Research Internships Conference
Hyperpolarized 129-Xe is an important resource in many fields of medical physics and MRI research. The physics of the efficient production of hyperpolarized 129-Xe is therefore equally worth investigation. The main process of hyperpolarizing 129-Xe is Spin Exchange Optical Pumping (SEOP) and is dependent on several physical factors that can be difficult to constantly change in a lab setting. Physical modelling of 129-Xe hyperpolarization allows for the more efficient testing of hyperpolarization physics in a wide array of experimental setups to better determine the optimal values for hyperpolarization. This research project attempted to create a working model for 129-Xe hyperpolarization …
Comparing Semi-Automated Segmentation Of Traditional-Resolution And High-Resolution Hyperpolarized 129xe Mri On Covid-19 Survivors, Tingting Wu
Undergraduate Student Research Internships Conference
Hyperpolarized gas MRI using inert gases like Xe is a valuable tool in visualizing lung ventilation in patients, and can be used as a longitudinal monitoring tool for patients with lung diseases. However, use of this method requires segmentation and quantification of parameters such as ventilation defect percentage (VDP), which is often very subjective depending on the observer. This study aimed to determine the accuracy and consistency of VDP calculation using the same MRI scans from COVID-19 patients, but with high resolution and low (traditional) resolution versions. Using a MATLAB script developed previously, it was found that in general, using …
Optimization Of Design Procedures For Delta Relaxation Enhanced Magnetic Resonance, Daniel J. Martire
Optimization Of Design Procedures For Delta Relaxation Enhanced Magnetic Resonance, Daniel J. Martire
Electronic Thesis and Dissertation Repository
Delta relaxation enhanced magnetic resonance (dreMR) is a magnetic resonance imaging (MRI) method that produces contrast based on longitudinal relaxation dispersion. Through modulation of the magnetic field using an actively-shielded, field-cycling insert coil, this technique increases probe specificity and suppresses remaining signal. However, significant improvements are needed. This thesis addresses two advancements in dreMR with a focus on optimizing design procedures. A general procedure was developed to design split power solenoid magnets. The procedure was then applied to the design of a switched-field exposure system. A coil was constructed and the method was validated. This procedure can be used for …
Hyperpolarized 129xe Magnetic Resonance Imaging Of Radiation-Induced Lung Injury, Ozkan Doganay
Hyperpolarized 129xe Magnetic Resonance Imaging Of Radiation-Induced Lung Injury, Ozkan Doganay
Electronic Thesis and Dissertation Repository
Lung cancer is the largest contributor to cancer-related mortality worldwide. Only 20% of stage III non-small cell lung cancer patients survive after 5-years post radiation therapy (RT). Although RT is an important treatment modality for lung cancer, it is limited by Radiation-Induced Lung Injury (RILI). RILI develops in two phases: (i) the early phase (days-weeks) referred to radiation pneumonitis (RP), and (ii) the late phase (months). There is a strong interest in early detection of RP using imaging to improve outcomes of RT for lung cancer. This thesis describes a promising approach based on 129Xe gas as a contrast …