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Full-Text Articles in Physics

Multivariate Statistical Methodologies Applied In Biomedical Raman Spectroscopy: Assessing The Validity Of Partial Least Squares Regression Using Simulated Model Datasets., Mark Keating Apr 2015

Multivariate Statistical Methodologies Applied In Biomedical Raman Spectroscopy: Assessing The Validity Of Partial Least Squares Regression Using Simulated Model Datasets., Mark Keating

Articles

Raman spectroscopy is fast becoming a valuable analytical tool in a number of biomedical scenarios, most notably disease diagnostics. Importantly, the technique has also shown increasing promise in the assessment of drug interactions on a cellular and subcellular level, particularly when coupled with multivariate statistical analysis. However, an important consideration, both with Raman spectroscopy and the associated statistical methodologies, is the accuracy of these techniques and more specifically the sensitivities which can be achieved and ultimately the limits of detection of the various methods. The purpose of this study is thus the construction of a model simulated data set with …


Vacuum Polarization On The Brane, Cormac Breen, Matthew Hewitt,, Elizabeth Winstanley, Adrian Ottewill Jan 2015

Vacuum Polarization On The Brane, Cormac Breen, Matthew Hewitt,, Elizabeth Winstanley, Adrian Ottewill

Articles

We compute the renormalized expectation value of the square of a massless, conformally coupled, quantum scalar field on the brane of a higher-dimensional black hole. Working in the AADD braneworld scenario, the extra dimensions are flat and we assume that the compactification radius is large compared with the size of the black hole. The four-dimensional on-brane metric corresponds to a slice through a higher-dimensional Schwarzschild-Tangherlini black hole geometry and depends on the number of bulk space-time dimensions. The quantum scalar field is in a thermal state at the Hawking temperature. An exact, closed-form expression is derived for the renormalized expectation …


Hamiltonian Approach To Internal Wave-Current Interactions In A Two-Media Fluid With A Rigid Lid, Alan Compelli, Rossen Ivanov Jan 2015

Hamiltonian Approach To Internal Wave-Current Interactions In A Two-Media Fluid With A Rigid Lid, Alan Compelli, Rossen Ivanov

Articles

We examine a two-media 2-dimensional fluid system consisting of a lower medium bounded underneath by a flatbed and an upper medium with a free surface with wind generated surface waves but considered bounded above by a lid by an assumption that surface waves have negligible amplitude. An internal wave driven by gravity which propagates in the positive x-direction acts as a free common interface between the media. The current is such that it is zero at the flatbed but a negative constant, due to an assumption that surface winds blow in the negative x-direction, at the lid. We are concerned …