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Multifunctional Nanopipette For Single Nanoparticles And Proteins Analysis, Popular Pandey
Multifunctional Nanopipette For Single Nanoparticles And Proteins Analysis, Popular Pandey
FIU Electronic Theses and Dissertations
Complex biological processes occur in the nanoscale (1-100 nm) regime. ‘DNA’ which is just 2 nm in dimension is a fundamental building block of all life. ‘Hemoglobin’, a blood protein that transports oxygen throughout our body is only 5 nm in diameter. Importantly, the structure, composition, and dynamics of these nanoscale entities determine their biological function. A slight alteration in the structure and composition can lead to the malfunction of the protein which is key to various diseases including cancer. Therefore, the single-molecule measurement approach is essential to characterize both the average properties and the rare …