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Full-Text Articles in Physics
Photoisomerizable Membrane Active Peptides, Cristina Ventura
Photoisomerizable Membrane Active Peptides, Cristina Ventura
Seton Hall University Dissertations and Theses (ETDs)
Membrane active peptides (MAPs) bind and partition into the cell membrane thus causing permeabilization. Many α-helical membrane active peptides contain central proline residues that distinguish the hydrophobic and hydrophilic faces of the helix. The proline induces a bend that produces a helix-hinge-helix motif. Mutation of these proline residues has a significant effect on the activity of the MAP. Azobenzene is a photoisomerizable molecule that switches from its trans to cis isomer upon excitation with ultraviolet (UV) light and from its cis to trans isomer upon excitation with visible light (VL). In this work it is hypothesized that the hinge function …
Molecular Dynamics Simulations Of Amphiphilic Molecules, Roger L. Mcmullen Jr.
Molecular Dynamics Simulations Of Amphiphilic Molecules, Roger L. Mcmullen Jr.
Seton Hall University Dissertations and Theses (ETDs)
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