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Full-Text Articles in Physics

Interactions Of Amyloid Peptides With Lipid Membranes, Yanxing Yang Dec 2022

Interactions Of Amyloid Peptides With Lipid Membranes, Yanxing Yang

Dissertations

The aggregation of amyloid proteins into fibrils is a hallmark of several diseases including Alzheimer’s (AD), Parkinson’s, and Type II diabetes. This aggregation process involves the formation of small size oligomers preceding the formation of insoluble fibrils. Recent studies have shown that these oligomers are more likely to be responsible for cell toxicity than fibrils. A possible mechanism of toxicity involves the interaction of oligomers with the cell membrane compromising its integrity. In particular, oligomers may form pore-like structures in the cell membrane affecting its permeability or they may induce lipid loss via a detergent-like effect. This dissertation aims to …


Methods For Bioconjugation Of Biochemical Sensors Based On Metallic Nanoparticles, Jacob Rolin Sep 2022

Methods For Bioconjugation Of Biochemical Sensors Based On Metallic Nanoparticles, Jacob Rolin

Summer Community of Scholars Posters (RCEU and HCR Combined Programs)

No abstract provided.


Annual Faculty Research Symposium 2022, Oakwood University Apr 2022

Annual Faculty Research Symposium 2022, Oakwood University

Proceedings

No abstract provided.