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Full-Text Articles in Other Physical Sciences and Mathematics
Understanding The Fundamental Molecular Mechanism Of Osteogenic Differentiation From Mesenchymal Stem Cells, Imelda Trejo, Hristo V. Kojouharov
Understanding The Fundamental Molecular Mechanism Of Osteogenic Differentiation From Mesenchymal Stem Cells, Imelda Trejo, Hristo V. Kojouharov
Applications and Applied Mathematics: An International Journal (AAM)
A mathematical model is presented to study the regulatory effects of growth factors in osteoblastogenesis. The model incorporates the interactions among mesenchymal stem cells, osteoblasts, and growth factors. The resulting system of nonlinear ordinary differential equations is studied analytically and numerically. Mathematical conditions for successful osteogenic differentiation and optimal osteoblasts population are formulated, which can be used in practice to accelerate bone formation. Numerical simulations are also presented to support the theoretical results and to explore different medical interventions to enhance osteoblastogenesis.
Bifurcation Analysis For Prey-Predator Model With Holling Type Iii Functional Response Incorporating Prey Refuge, Lazaar Oussama, Mustapha Serhani
Bifurcation Analysis For Prey-Predator Model With Holling Type Iii Functional Response Incorporating Prey Refuge, Lazaar Oussama, Mustapha Serhani
Applications and Applied Mathematics: An International Journal (AAM)
In this paper, we carried out the bifurcation analysis for a Lotka-Volterra prey-predator model with Holling type III functional response incorporating prey refuge protecting a constant proportion of the preys. We study the local bifurcation considering the refuge constant as a parameter. From the center manifold equation, we establish a transcritical bifurcation for the boundary equilibrium. In addition, we prove the occurrence of Hopf bifurcation for the homogeneous equilibrium. Moreover, we give the radius and period of the unique limit cycle for our system