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Medicine and Health Sciences

Modeling

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Full-Text Articles in Other Physical Sciences and Mathematics

Forecasting Longitudinal Changes In Oropharyngeal Tumor Volume, Position, And Morphology During Image-Guided Radiation Therapy, Adam D. Yock May 2014

Forecasting Longitudinal Changes In Oropharyngeal Tumor Volume, Position, And Morphology During Image-Guided Radiation Therapy, Adam D. Yock

Dissertations & Theses (Open Access)

The purpose of this work was to generate, evaluate, and compare models that predict longitudinal changes in oropharyngeal tumor volume, position, and morphology during radiation therapy.

One volume, one position, and two morphology (size, shape, and position) feature vectors were used to describe 35 oropharyngeal gross tumor volumes (GTVs) during radiation therapy. The two morphology feature vectors comprised the coordinates of the GTV centroids and one of two shape descriptors. One shape descriptor was based on radial distances between the GTV centroid and 614 surface landmarks. The other was based on a spherical harmonic decomposition of these distances. For a …