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Inhibition Of Erythrocyte Δ- Aminolevulinic Acid Dehydratase (Alad) Activity In Fish From Waters Affects By Lead Smelters, Christopher J. Schmitt, Colleen A. Caldwell, Bill Olsen, Dave Serdar

United States Geological Survey: Staff Publications

We assessed the effects on fish of lead (Pb) released to streams by smelters located in Trail, BC (Canada), E. Helena, MT, Herculaneum, MO, and Glover, MO. Fish were collected by electrofishing from sites located downstream of smelters and from reference sites. Blood from each fish was analyzed for δ-aminolevulinic acid dehydratase (ALAD) activity and hemoglobin (Hb), and samples of blood, liver, or carcass were analyzed for Pb, zinc (Zn), or both. Fish collected downstream of all four smelters sites had elevated Pb concentrations, decreased ALAD activity, or both relative to their respective reference sites. At E. Helena, fish from …