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Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen Jan 2024

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …


Applications Of Nonstandard Analysis In Probability And Measure Theory, Irfan Alam May 2021

Applications Of Nonstandard Analysis In Probability And Measure Theory, Irfan Alam

LSU Doctoral Dissertations

This dissertation broadly deals with two areas of probability theory and investigates how methods from nonstandard analysis may provide new perspectives in these topics. In particular, we use nonstandard analysis to prove new results in the topics of limiting spherical integrals and of exchangeability.

In the former area, our methods allow us to represent finite dimensional Gaussian measures in terms of marginals of measures on hyperfinite-dimensional spheres in a certain strong sense, thus generalizing some previously known results on Gaussian Radon transforms as limits of spherical integrals. This first area has roots in the kinetic theory of gases, which is …