Discrete Mathematics and Combinatorics Commons^™

Behavior Of Petrie Lines In Certain Edge-Transitive Graphs, Ruby A. Chick

Math Theses

We survey the construction and classification of one-, two- and infinitely-ended members of a class of highly symmetric, highly connected infinite graphs. In addition, we pose a conjecture concerning the relationship between the Petrie lines and ends of some infinitely-ended members of this class.

Network Modeling Of Infectious Disease: Transmission, Control And Prevention, Christina M. Chandler

Honors College Theses

Many factors come into play when it comes to the transmission of infectious diseases. In disease control and prevention, it is inevitable to consider the general population and the relationships between individuals as a whole, which calls for advanced mathematical modeling approaches.

We will use the concept of network flow and the modified Ford-Fulkerson algorithm to demonstrate the transmission of infectious diseases over a given period of time. Through our model one can observe what possible measures should be taken or improved upon in the case of an epidemic. We identify key nodes and edges in the resulted network, which …

On T-Restricted Optimal Rubbling Of Graphs, Kyle Murphy

Electronic Theses and Dissertations

For a graph G = (V;E), a pebble distribution is defined as a mapping of the vertex set in to the integers, where each vertex begins with f(v) pebbles. A pebbling move takes two pebbles from some vertex adjacent to v and places one pebble on v. A rubbling move takes one pebble from each of two vertices that are adjacent to v and places one pebble on v. A vertex x is reachable under a pebbling distribution f if there exists some sequence of rubbling and pebbling moves that places a pebble on x. A pebbling distribution where every …

Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri

Theses and Dissertations

miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …