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Full-Text Articles in Discrete Mathematics and Combinatorics

Tropical Algebra, Graph Theory, & Foreign Exchange Arbitrage, Bradley A. Mason May 2017

Tropical Algebra, Graph Theory, & Foreign Exchange Arbitrage, Bradley A. Mason

Senior Honors Projects, 2010-2019

We answer the question, given n currencies and k trades, how can a maximal arbitrage opportunity be found and what is its value? To answer this question, we use techniques from graph theory and employ a max-plus algebra (commonly known as tropical algebra). Further, we show how the tropical eigenvalue of a foreign exchange rate matrix relates to arbitrage among the currencies and can be found algorithmically. We finish by employing time series techniques to study the stability of maximal, high-currency arbitrage opportunities.


Differentiating Between A Protein And Its Decoy Using Nested Graph Models And Weighted Graph Theoretical Invariants, Hannah E. Green May 2017

Differentiating Between A Protein And Its Decoy Using Nested Graph Models And Weighted Graph Theoretical Invariants, Hannah E. Green

Electronic Theses and Dissertations

To determine the function of a protein, we must know its 3-dimensional structure, which can be difficult to ascertain. Currently, predictive models are used to determine the structure of a protein from its sequence, but these models do not always predict the correct structure. To this end we use a nested graph model along with weighted invariants to minimize the errors and improve the accuracy of a predictive model to determine if we have the correct structure for a protein.


Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri Jan 2017

Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri

Theses and Dissertations

miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …


Dynamics Of Gene Networks In Cancer Research, Paul Scott Jan 2017

Dynamics Of Gene Networks In Cancer Research, Paul Scott

Electronic Theses and Dissertations

Cancer prevention treatments are being researched to see if an optimized treatment schedule would decrease the likelihood of a person being diagnosed with cancer. To do this we are looking at genes involved in the cell cycle and how they interact with one another. Through each gene expression during the life of a normal cell we get an understanding of the gene interactions and test these against those of a cancerous cell. First we construct a simplified network model of the normal gene network. Once we have this model we translate it into a transition matrix and force changes on …