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Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

2008

Georgia State University

Bootstrap

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Full-Text Articles in Mathematics

An Analysis Of Fourier Transform Infrared Spectroscopy Data To Predict Herpes Simplex Virus 1 Infection, Patrick D. Champion Nov 2008

An Analysis Of Fourier Transform Infrared Spectroscopy Data To Predict Herpes Simplex Virus 1 Infection, Patrick D. Champion

Mathematics Theses

The purpose of this analysis is to evaluate the usefulness of Fourier Transform Infrared (FTIR) spectroscopy in the detection of Herpes Simplex Virus 1 (hsv1) infection at an early stage. The raw absorption values were standardized to eliminate inter-sampling error. Wilcoxon-Mann-Whitney (WMW) statistic's Z score was calculated to select significant spectral regions. Partial least squares modeling was performed because of multicollinearity. Kolmogorov-Smirnov statistic showed models for healthy tissues from different time groups were not from same distribution. The additional 24 hour dataset was evaluated using the following methods. Variables were selected by WMW Z score. Difference of Composites statistic, DC, …


Bootstrap And Empirical Likelihood-Based Semi-Parametric Inference For The Difference Between Two Partial Aucs, Xin Huang Jul 2008

Bootstrap And Empirical Likelihood-Based Semi-Parametric Inference For The Difference Between Two Partial Aucs, Xin Huang

Mathematics Theses

With new tests being developed and marketed, the comparison of the diagnostic accuracy of two continuous-scale diagnostic tests are of great importance. Comparing the partial areas under the receiver operating characteristic curves (pAUC) is an effective method to evaluate the accuracy of two diagnostic tests. In this thesis, we study the semi-parametric inference for the difference between two pAUCs. A normal approximation for the distribution of the difference between two pAUCs has been derived. The empirical likelihood ratio for the difference between two pAUCs is defined and its asymptotic distribution is shown to be a scaled chi-quare distribution. Bootstrap and …