Mathematics Commons^™

Mitigation Impact Of Statewide Non-Pharmaceutical Policies On Covid-19: An Application Of Infectious Disease Transmission Model And Partially Observed Markov Process To New Mexico, Xingya Ma

Mathematics & Statistics ETDs

This thesis is an application of epidemiological models for infectious disease transmission and the use of partially observed Markov process (POMP) for model fitting. It focuses on COVID-19 pandemic in the state of New Mexico. The analysis covered March 2020 to June 2021. Daily data of COVID19 cases and deaths and a daily index of eleven statewide government non-pharmaceutical intervention (NPI) policies were collected from six public sources and were validated. These data were integrated through the Susceptible-Exposed-Infected-Removed (SEIR) model. Estimated daily transmission rates between the model compartments quantify the impact of the mitigation policies, and show that transmission rates …

Convexity Of Regularized Optimal Transport Dissimilarity Measures For Signed Signals, Christian P. Fowler

Mathematics & Statistics ETDs

Debiased Sinkhorn divergence (DS divergence) is a distance function of

regularized optimal transport that measures the dissimilarity between two

probability measures of optimal transport. This thesis analyzes the advantages of

using DS divergence when compared to the more computationally expensive

Wasserstein distance as well as the classical Euclidean norm. Specifically, theory

and numerical experiments are used to show that Debiased Sinkhorn divergence

has geometrically desirable properties such as maintained convexity after data

normalization. Data normalization is often needed to calculate Sinkhorn

divergence as well as Wasserstein distance, as these formulas only accept

probability distributions as inputs and do not directly …

Statistical Methods For Differential Gene Expression Analysis Under The Case-Cohort Design, Lidong Wang

Mathematics & Statistics ETDs

Differential gene expression analysis has the potential to discover candidate biomarkers, therapeutic targets, and gene signatures. How to save money when using an unaffordable sample is a practical question. The case-cohort (CCH) study design can blend the economy of case-control studies with the advantages of cohort studies. But it has not been seen in the medical research literature where high-throughput genomic data were involved.

A score test does not need to fit the Cox PH model iteratively; hence, it can save computing time and avoid potential convergence issues. We developed a score test under the CCH design to identify DEGs …

Functional Data Analysis Of Covid-19, Nichole L. Fluke

Mathematics & Statistics ETDs

This thesis deals with Functional Data Analysis (FDA) on COVID data. The Data involves counts for new COVID cases, hospitalized COVID patients, and new COVID deaths. The data used is for all the states and regions in the United States. The data starts in March 1^st, 2020 and goes through March 31^st, 2021. The FDA smooths the data and looks to see if there are similarities or differences between the states and regions in the data. The data also shows which states and regions stand out from the others and which ones are similar. Also shown …

Music Genre Classification By Convolutional Neural Networks, Usame Suud

Mathematics & Statistics ETDs

In today’s world, deep learning models are widely used in a variety of fields. Audio

applications include speech recognition, audio classification, and music information

retrieval. In this paper, we will focus on the classification of music genres using an

artificial neural network. The development of audio machine learning techniques has

created an independence from traditional, more time-consuming signal processing

techniques. Starting with raw audio data, we will gain an understanding of what

audio is and its digital representation. Then, the focus will be on obtaining frequency

information from audio signals through the use of spectrograms. Transforming the

spectrograms into the …

Determining The Idealizers Of Principal Monomial Ideals Over A Rational Normal Curve, Perla A. Maldonado Cortez

Mathematics & Statistics ETDs

Given an ideal J generated by an element of the form sm1 tm2 , where
m1 ≥ 2 and m2 ≥ 0, we illustrate how to compute the idealizer I(J) over the ring
of the rational normal curve of degree n and we give a formula for it using the
graded pieces of the sets of differential operators.

Machine Learning Model Comparison And Arma Simulation Of Exhaled Breath Signals Classifying Covid-19 Patients, Aaron Christopher Segura

Mathematics & Statistics ETDs

This study compared the performance of machine learning models in classifying COVID-19 patients using exhaled breath signals and simulated datasets. Ground truth classification was determined by the gold standard Polymerase Chain Reaction (PCR) test results. A residual bootstrapped method generated the simulated datasets by fitting signal data to Autoregressive Moving Average (ARMA) models. Classification models included neural networks, k-nearest neighbors, naïve Bayes, random forest, and support vector machines. A Recursive Feature Elimination (RFE) study was performed to determine if reducing signal features would improve the classification models performance using Gini Importance scoring for the two classes. The top 25% of …

Robust Uncertainty Quantification With Analysis Of Error In Standard And Non-Standard Quantities Of Interest, Zachary Stevens

Mathematics & Statistics ETDs

This thesis derives two Uncertainty Quantification (UQ) methods for differential equations that depend on random parameters: (\textbf{i}) error bounds for a computed cumulative distribution function (\textbf{ii}) a multi-level Monte Carlo (MLMC) algorithm with adaptively refined meshes and accurately computed stopping-criteria. Both UQ approaches utilize adjoint-based \textit{a posteriori} error analysis in order to accurately estimate the error in samples of numerically approximated quantities of interest. The adaptive MLMC algorithm developed in this thesis relies on the adjoint-based error analysis to adaptively create meshes and accurately monitor a stopping criteria. This is in contrast to classical MLMC algorithms which employ either a …

Effect Of Phylogeny Misestimation On Estimating Trait Evolution Parameters, Tabytha Ariel Perez

Mathematics & Statistics ETDs

Biologists are interested in estimating trait evolution models from phylogenies. However, phylogenies are imperfectly estimated, generally from DNA sequence data. In this study, true phylogenies are simulated to understand whether errors in phylogeny estimation affect inference of the trait evolution model. Given the tree, DNA sequences as well as traits are then simulated from the true phylogeny; both are simulated independently from the other. After the simulation, the DNA sequences were used to estimate trees using the UPGMA method without utilizing the trait information. The estimated trees combined with the traits are used to infer the evolutionary trait models, specifically …

The Obata First Eigenvalue Theorem On A Seven Dimensional Quaternionic Contact Manifold, Abdelrahman Mohamed

Mathematics & Statistics ETDs

We prove an Obata-type rigidity result for the first eigenvalue of the sub-Laplacian on a compact seven dimensional quaternionic contact (QC) manifold which satisfies a Lichnerowicz-type bound on its QC-Ricci tensor, and has a non-negative Paneitz P -function. In particular, under the stated conditions, the lowest possible eigenvalue of the sub-Laplacian is achieved if and only if the manifold is QC-equivalent to the standard 3-Sasakian sphere.

Applications Of Machine Learning Algorithms In Materials Science And Bioinformatics, Mohammed Quazi

Mathematics & Statistics ETDs

The piezoelectric response has been a measure of interest in density functional theory (DFT) for micro-electromechanical systems (MEMS) since the inception of MEMS technology. Piezoelectric-based MEMS devices find wide applications in automobiles, mobile phones, healthcare devices, and silicon chips for computers, to name a few. Piezoelectric properties of doped aluminum nitride (AlN) have been under investigation in materials science for piezoelectric thin films because of its wide range of device applicability. In this research using rigorous DFT calculations, high throughput ab-initio simulations for 23 AlN alloys are generated.

This research is the first to report strong enhancements of piezoelectric properties …

Sparse Spectral-Tau Method For The Two-Dimensional Helmholtz Problem Posed On A Rectangular Domain, Gabriella M. Dalton

Mathematics & Statistics ETDs

Within recent decades, spectral methods have become an important technique in numerical computing for solving partial differential equations. This is due to their superior accuracy when compared to finite difference and finite element methods. For such spectral approximations, the convergence rate is solely dependent on the smoothness of the solution yielding the potential to achieve spectral accuracy. We present an iterative approach for solving the two-dimensional Helmholtz problem posed on a rectangular domain subject to Dirichlet boundary conditions that is well-conditioned, low in memory, and of sub-quadratic complexity. The proposed approach spectrally approximates the partial differential equation by means of …

Eigenfunction Restriction Estimates For Curves With Nonvanishing Geodesic Curvatures In Compact Riemannian Surfaces With Nonpositive Sectional Curvatures, Chamsol Park

Mathematics & Statistics ETDs

For 2 ≤ p < 4, we study the Lp norms of restrictions of eigenfunctions of the Laplace-Beltrami operator on smooth compact 2-dimensional Riemannian manifolds. Burq, G\´erard, and Tzvetkov [12], and Hu [21] found eigenfunction restriction estimates for a curve with nonvanishing geodesic curvatures. We will explain how the proof of the known estimates helps us to consider the case where the given smooth compact Riemannian manifold has nonpositive sectional curvatures. For p = 4, we will also obtain a logarithmic analogous estimate, by using arguments in Xi and Zhang [37], Sogge [33], and Bourgain [10]. At the end of this dissertation, we will talk about a future work, which is a follow up study for higher dimensional analogues of the above curve cases.