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Statistics and Probability

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Error rate

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Family-Wise Error Rate Control In Quantitative Trait Loci (Qtl) Mapping And Gene Ontology Graphs With Remarks On Family Selection, Garrett Saunders May 2014

Family-Wise Error Rate Control In Quantitative Trait Loci (Qtl) Mapping And Gene Ontology Graphs With Remarks On Family Selection, Garrett Saunders

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

One of the great aims of statistics, the science of collecting, analyzing, and interpreting data, is to protect against the probability of falsely rejecting an accepted claim, or hypothesis, given observed data stemming from some experiment. This is generally known as protecting against a Type I Error, or controlling the Type I Error rate. The extension of this protection against Type I Errors to the situation where thousands upon thousands of hypotheses are examined simultaneously is known as multiple hypothesis testing. This dissertation presents an improvement to an existing multiple hypothesis testing approach, the Focus Level method, specific to gene …