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United States Geological Survey: Staff Publications

2014

Pharmaceuticals

Articles 1 - 2 of 2

Full-Text Articles in Earth Sciences

Riverbank Filtration Potential Of Pharmaceuticals In A Wastewater-Impacted Stream, Paul M. Bradley, Larry B. Barber, Joesph W. Duris, William T. Foreman, Edward T. Furlong, Laura E. Hubbard, Kasey J. Hutchinson, Steffanie H. Keefe, Dana W. Kolpin Jan 2014

Riverbank Filtration Potential Of Pharmaceuticals In A Wastewater-Impacted Stream, Paul M. Bradley, Larry B. Barber, Joesph W. Duris, William T. Foreman, Edward T. Furlong, Laura E. Hubbard, Kasey J. Hutchinson, Steffanie H. Keefe, Dana W. Kolpin

United States Geological Survey: Staff Publications

Pharmaceutical contamination of shallow groundwater is a substantial concern in effluent-dominated streams, due to high aqueous mobility, designed bioactivity, and effluent-driven hydraulic gradients. In October and December 2012, effluent contributed approximately 99% and 71%, respectively, to downstream flow in Fourmile Creek, Iowa, USA. Strong hydrologic connectivity was observed between surface-water and shallow-groundwater. Carbamazepine, sulfamethoxazole, and immunologically related compounds were detected in groundwater at greater than 0.02 mg L^-1 at distances up to 6 m from the stream bank. Direct aqueous-injection HPLC-MS/MS revealed 43% and 55% of 110 total pharmaceutical analytes in surface-water samples in October and December, respectively, with 16% …


Exposure And Food Web Transfer Of Pharmaceuticals In Ospreys (Pandion Haliaetus): Predictive Model And Empirical Data, Rebecca S. Lazarus, Barnett A. Rattner, Bryan W. Brooks, Bowen Du, Peter C. Mcgowan, Vicki S. Blazer, Mary Ann Ottinger Jan 2014

Exposure And Food Web Transfer Of Pharmaceuticals In Ospreys (Pandion Haliaetus): Predictive Model And Empirical Data, Rebecca S. Lazarus, Barnett A. Rattner, Bryan W. Brooks, Bowen Du, Peter C. Mcgowan, Vicki S. Blazer, Mary Ann Ottinger

United States Geological Survey: Staff Publications

The osprey (Pandion haliaetus) is a well‐known sentinel of environmental contamination, yet no studies have traced pharmaceuticals through the water–fish–osprey food web. A screening‐level exposure assessment was used to evaluate the bioaccumulation potential of 113 pharmaceuticals and metabolites, and an artificial sweetener in this food web. Hypothetical concentrations in water reflecting “wastewater effluent dominated” or “dilution dominated” scenarios were combined with pH‐specific bioconcentration factors (BCFs) to predict uptake in fish. Residues in fish and osprey food intake rate were used to calculate the daily intake (DI) of compounds by an adult female osprey. Fourteen pharmaceuticals and a drug …