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Mining Data On Traumatic Brain Injury With Reconstructability Analysis, Martin Zwick, Nancy Carney, Rosemary Nettleton

Systems Science Faculty Publications and Presentations

This paper reports the analysis of data on traumatic brain injury using a probabilistic graphical modeling technique known as reconstructability analysis (RA). The analysis shows the flexibility, power, and comprehensibility of RA modeling, which is well-suited for mining biomedical data. One finding of the analysis is that education is a confounding variable for the Digit Symbol Test in discriminating the severity of concussion; another - and anomalous - finding is that previous head injury predicts improved performance on the Reaction Time test. This analysis was exploratory, so its findings require follow-on confirmatory tests of their generalizability.