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Full-Text Articles in Systems Architecture

Design And Implementation Of A Stand-Alone Tool For Metabolic Simulations, Milad Ghiasi Rad Dec 2017

Design And Implementation Of A Stand-Alone Tool For Metabolic Simulations, Milad Ghiasi Rad

Department of Computer Science and Engineering: Dissertations, Theses, and Student Research

In this thesis, we present the design and implementation of a stand-alone tool for metabolic simulations. This system is able to integrate custom-built SBML models along with external user’s input information and produces the estimation of any reactants participating in the chain of the reactions in the provided model, e.g., ATP, Glucose, Insulin, for the given duration using numerical analysis and simulations. This tool offers the food intake arguments in the calculations to consider the personalized metabolic characteristics in the simulations. The tool has also been generalized to take into consideration of temporal genomic information and be flexible for simulation …


Characterizing And Improving Power And Performance In Hpc Networks, Taylor L. Groves May 2017

Characterizing And Improving Power And Performance In Hpc Networks, Taylor L. Groves

Computer Science ETDs

Networks are the backbone of modern HPC systems. They serve as a critical piece of infrastructure, tying together applications, analytics, storage and visualization. Despite this importance, we have not fully explored how evolving communication paradigms and network design will impact scientific workloads. As networks expand in the race towards Exascale (1×10^18 floating point operations a second), we need to reexamine this relationship so that the HPC community better understands (1) characteristics and trends in HPC communication; (2) how to best design HPC networks to save power or enhance the performance; (3) how to facilitate scalable, informed, and dynamic decisions within …