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Theses and Dissertations--Computer Science

Clustering

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Context Aware Privacy Preserving Clustering And Classification, Nirmal Thapa Jan 2013

Context Aware Privacy Preserving Clustering And Classification, Nirmal Thapa

Theses and Dissertations--Computer Science

Data are valuable assets to any organizations or individuals. Data are sources of useful information which is a big part of decision making. All sectors have potential to benefit from having information. Commerce, health, and research are some of the fields that have benefited from data. On the other hand, the availability of the data makes it easy for anyone to exploit the data, which in many cases are private confidential data. It is necessary to preserve the confidentiality of the data. We study two categories of privacy: Data Value Hiding and Data Pattern Hiding. Privacy is a huge concern …


Computer Methods For Pre-Microrna Secondary Structure Prediction, Dianwei Han Jan 2012

Computer Methods For Pre-Microrna Secondary Structure Prediction, Dianwei Han

Theses and Dissertations--Computer Science

This thesis presents a new algorithm to predict the pre-microRNA secondary structure. An accurate prediction of the pre-microRNA secondary structure is important in miRNA informatics. Based on a recently proposed model, nucleotide cyclic motifs (NCM), to predict RNA secondary structure, we propose and implement a Modified NCM (MNCM) model with a physics-based scoring strategy to tackle the problem of pre-microRNA folding. Our microRNAfold is implemented using a global optimal algorithm based on the bottom-up local optimal solutions.

It has been shown that studying the functions of multiple genes and predicting the secondary structure of multiple related microRNA is more important …