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Full-Text Articles in Computer Sciences

A Locus-Based Paradigm For Generating Systems Biological Inferences From Large Scale Functional Genomics Datasets, Ajish Dominic George Jan 2009

A Locus-Based Paradigm For Generating Systems Biological Inferences From Large Scale Functional Genomics Datasets, Ajish Dominic George

Legacy Theses & Dissertations (2009 - 2024)

Genomics data is growing at a exponential rate. The ability to integrate new results with existing knowledge about genomic biology is rapidly becoming the limiting factor as there no universal language with which to describe genomic functional elements. To integrate and compare new and existing genomic data, we define our basic functional unit of a genome to be a locus -- a set of positional coordinates along any genome with an arbitrary amount of functional annotations attached. The locus concept enables addressing genomic elements and annotations at any level of granularity from entire swaths of chromosomes to single base-positions. We …


Machine Learned Melody Matching Using Strictly Relative Musical Abstractions, Michael Joseph Kolta Jan 2009

Machine Learned Melody Matching Using Strictly Relative Musical Abstractions, Michael Joseph Kolta

Legacy Theses & Dissertations (2009 - 2024)

We implement and evaluate a machine learning approach to improve systems for searching a database of music via melodic sample. We explore symbolic and aural input queries and test our prototypes with extensive user surveys. Our main contribution is to combine the following four elements. First is to create a unique musical abstraction that accounts for both pitch and rhythm in a relative manner. Second, our system allows for approximate matching of imperfect queries via the utilization of the Smith-Waterman algorithm that was originally designed for approximate matching of molecular subsequences, such as DNA samples. Third is to design our …


Bootstrapping Events And Relations From Text, Ting Liu Jan 2009

Bootstrapping Events And Relations From Text, Ting Liu

Legacy Theses & Dissertations (2009 - 2024)

Information Extraction (IE) is a technique for automatically extracting structured data from text documents. One of the key analytical tasks is extraction of important and relevant information from textual sources. While information is plentiful and readily available, from the Internet, news services, media, etc., extracting the critical nuggets that matter to business or to national security is a cognitively demanding and time consuming task. Intelligence and business analysts spend many hours poring over endless streams of text documents pulling out reference to entities of interest (people, locations, organizations) as well as their relationships as reported in text. Such extracted "information …