Computer Sciences Commons^™

Automation Process For Morphometric Analysis Of Volumetric Ct Data From Pulmonary Vasculature In Rats, Rahul Shingrani, Gary S. Krenz, Robert Molthen

Mathematics, Statistics and Computer Science Faculty Research and Publications

With advances in medical imaging scanners, it has become commonplace to generate large multidimensional datasets. These datasets require tools for a rapid, thorough analysis. To address this need, we have developed an automated algorithm for morphometric analysis incorporating A Visualization Workshop computational and image processing libraries for three-dimensional segmentation, vascular tree generation and structural hierarchical ordering with a two-stage numeric optimization procedure for estimating vessel diameters. We combine this new technique with our mathematical models of pulmonary vascular morphology to quantify structural and functional attributes of lung arterial trees. Our physiological studies require repeated measurements of vascular structure to determine …