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Full-Text Articles in Computer Sciences
Functional Role Of The N-Terminal Domain In Connexin 46/50 By In Silico Mutagenesis And Molecular Dynamics Simulation, Umair Khan
University Honors Theses
Connexins form intercellular channels known as gap junctions that facilitate diverse physiological roles, from long-range electrical and chemical coupling to nutrient exchange. Recent structural studies on Cx46 and Cx50 have defined a novel and stable open state and implicated the amino-terminal (NT) domain as a major contributor to functional differences between connexin isoforms. This thesis presents two studies which use molecular dynamics simulations with these new structures to provide mechanistic insight into the function and behavior of the NTH in Cx46 and Cx50. In the first, residues in the NTH that differ between Cx46 and Cx50 are swapped between the …
Group Theory Visualized Through The Rubik's Cube, Ashlyn Okamoto
Group Theory Visualized Through The Rubik's Cube, Ashlyn Okamoto
University Honors Theses
In my thesis, I describe the work done to implement several Group Theory concepts in the context of the Rubik’s cube. A simulation of the cube was constructed using Processing-Java and with help from a YouTube series done by TheCodingTrain. I reflect on the struggles and difficulties that came with creating this program along with the inspiration behind the project. The concepts that are currently implemented at this time are: Identity, Associativity, Order, and Inverses. The functionality of the cube is described as it moves like a regular cube but has extra keypresses that demonstrate the concepts listed. Each concept …