Computer Sciences Commons^™

Signet: A Neural Network Architecture For Predicting Protein-Protein Interactions, Muhammad S. Ahmed

Electronic Thesis and Dissertation Repository

The study of protein-protein interactions (PPI) is critically important within the field of Molecular Biology, as proteins facilitate key organismal functions including the maintenance of both cellular structure and function. Current experimental methods for elucidating PPIs are greatly hindered by large operating costs, lengthy wait times, as well as low accuracy. The recent development of computational PPI predicting techniques has worked to address many of these issues. Despite this, many of these methods utilize over-engineered features and naive learning algorithms. With the recent advances in Machine Learning and Artificial Intelligence, we attempt to view this problem through a novel, deep …