Chemistry Commons^™

In-Column Polymer Modifications: Advancing Polymer Bonded Phases, Alexis G. Huckabee

Open Access Dissertations

Glycosylation is the most common post-translational modification affecting protein activities, including delivery to cell surface, binding affinity, and mediating different physiological effects. Separations of glycoproteins and their glycoforms are essential for drug discovery and development, identification of potential disease biomarkers and quality control. The efficiency of glycoprotein separations is limited by the bonded phases, requiring advances in chromatographic materials. Such advances would improve resolution, allowing for more species to be isolated from a mixture and studied.

Our group found that submicrometer nonporous silica stationary phases with tethered polymer chains (acrylamide) give excellent hydrophilic liquid chromatography (HILIC), a common method used …

Silver-Polymer Nanocomposites, Anita N. Paul

Electronic Theses and Dissertations

The objective of this research was the development of an efficient method for the preparation of silver-polymer nanocomposites containing finely dispersed silver nanoparticles. The surface of nanosilver was functionalized by thiolation with 2-aminoethanethiol. Amino-modified nanosilver was covalently bonded to polyacrylic acid, biodegradable polymers like acid terminated polylactic acid, ester terminated poly(DL-lactide-co-glycolide) and acid terminated poly(DL lactide-co-glycolide) in the presence of diisopropylcarbodiimide by carbodiimide method. Esterification of the carboxyl groups of Ag-polyacrylic acid by hydrochloric acid in methanol resulted in the formation of a stable colloidal dispersion of Ag nanoparticles in the polymer matrix. It was observed that not just acid …

To Bend Or Not To Bend – Are Heteroatom Interactions Within Conjugated Molecules Effective In Dictating Conformation And Planarity?, Gary Conboy, Howard J. Spencer, Enrico Angioni, Alexander L. Kanibolotsky, Neil J. Findlay, Simon J. Coles, Claire Wilson, Mateusz B. Pitak, Chad Risko, Veaceslav Coropceanu, Jean-Luc Brédas, Peter J. Skabara

Chemistry Faculty Publications

We consider the roles of heteroatoms (mainly nitrogen, the halogens and the chalcogens) in dictating the conformation of linear conjugated molecules and polymers through non-covalent intramolecular interactions. Whilst hydrogen bonding is a competitive and sometimes more influential interaction, we provide unambiguous evidence that heteroatoms are able to determine the conformation of such materials with reasonable predictability.

Biodegradable Copolymers Made With Magnesium Complexes, Reile M. Slattery, Joseph M. Fritsch

Seaver College Research And Scholarly Achievement Symposium

In this study, a bis-ligated magnesium complex was used to initiate the ring opening copolymerization of L-lactide (L-LA) and ϵ-caprolatone (ϵCL) and the isolated polymeric materials were characterized with NMR spectroscopy. First, the simultaneous feeding of both monomers resulted in the synthesis of homopolymer poly-lactic acid (PLA). Polymerization experiments with sequential addition of L-LA and ϵCL yielded surprising results. The ring opening polymerization of ϵCL yielded poly-caprolactone (PCL) which with the addition of L-LA yielded a di-block copolymer of PCL and PLA. The presence of the two homopolymer blocks in the copolymer was identified with ¹³C NMR where …

A 1-D Coordination Polymer Route To Catalytically Active Co@C Nanoparticles, Anand Pariyar, Siddharth Gopalakrishnan, Joseph Stansbery, Rajankumar L. Patel, Xinhua Liang, Nikolay Nikolaevich Gerasimchuk, Amitava Choudhury

Chemistry Faculty Research & Creative Works

Pyrolysis of a 1-D polymeric cobalt(ii) coordination complex ([Co(BDC)(Mim)₂]_n, H₂BDC = benzenedicarboxylic acid; Mim = N-methylimidazole) results in the formation of carbon embedded fcc cobalt nanoparticle composites, Co@C. The as-prepared Co@C shows an agglomerated secondary structure with a highly embedded carbon shell comprising of cobalt nanoparticles of 20-100 nm. These Co@C particles show excellent catalytic activity in the reduction of nitrophenol to aminophenol, studied as a model reaction, and evolves as a promising candidate for the gas phase reduction process.

Chemistry And Biochemistry News, Georgia Southern University

Department of Chemistry and Biochemistry News (2015-2023)

• Brawns of Brainy Polymers
• You Can't Always Eat What You Want
• Biomaterials Serves as Inspiration for the Youth
• BSL-2 Lab Unique to GSU Is Up and Running
• Polymer Coatings Program at GSU Is Opening Doors
• Professor Wins Prestigious Rising Star Award

Synthesis, Characterization, And Polymerization Of Sulfonamide Based Bifunctional Monomers, Brady Hall

Browse all Theses and Dissertations

A series of bifunctional monomers based on N,N-diallylbenzenesulfonamides with varying groups on the benzene moiety were investigated. The main goal of this project was to polymerize these monomers using radical and acyclic diene metathesis (ADMET) polymerization methods to polymerize through the allyl groups, and nucleophilic aromatic substitution (SNAr) to polymerize through the fluorine groups on the phenyl ring. Using phenyl substituted benzenesulfonyl chloride derivatives as a starting material, a series of N,N-diallylbenzenesulfonamide derivatives were prepared. The ADMET and radical cyclopolymerizations were monitored by 1H NMR spectroscopy, observing the disappearance of signals for the allyl groups in both, and the appearance …

Synthesis And Characterization Of Functionalized Poly(Arylene Ether Sulfone)S Using Click Chemistry, Kavitha Neithikunta

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Poly(arylene ether sulfone)s with pendent aryl iodide group was successfully synthesized via Nucleophilic aromatic polycondensation of 1-(3,5-difluorophenyl sulfonyl)-4-iodobenzene using 4,4’-difluorodiphenylsulfone (DFDPS) and Bisphenol A in the ratio 25:75:100. Iodo monomer was prepared by reacting 3,5-difluorodiphenyl sulfone with N-iodo succinimide (NIS). Using GC/MS and NMR spectroscopy, the quantitative analysis was done to this monomer. Modification was done to iodo copolymer using sodium azide and copper sulfate as catalyst to form azide copolymer. Further modification of the azide copolymer to triazole copolymers via Click Chemistry using different alkynes such as 1-octyne, phenyl acetylene, propargyl alcohol and acetylenedicarboxylic acid. Polymers characterization was done …