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Full-Text Articles in Chemistry

Visualization For Better Learning In Chem 120, Ngoc (Valerie) Tran, Jeff Hansen Ph.D Oct 2022

Visualization For Better Learning In Chem 120, Ngoc (Valerie) Tran, Jeff Hansen Ph.D

Annual Student Research Poster Session

Many concepts in organic chemistry relate to spatial reasoning and the ability to translate two-dimensional representations into a three-dimensional mental image. It is critical that students gain a thorough understanding of visualizing atoms, orbitals and their interactions in three dimensions. By developing an E-book with computer graphics, 3D animations, H5P films, and online apps, we hope to enhance Depauw students' learning experiences in the CHEM 120 course. In this project, we would like to demonstrate 3D representations of chemical concepts to help students form these 3D mental images from a 2D surface. The process includes concept developing, storyboarding, 2D and …


High Performance Liquid Chromatography (Hplc) For Ampicillin And Cefuroxime, Patrick Mcinerney, Richard Martoglio Oct 2022

High Performance Liquid Chromatography (Hplc) For Ampicillin And Cefuroxime, Patrick Mcinerney, Richard Martoglio

Annual Student Research Poster Session

Appropriate levels of an active pharmaceutical ingredient (API) in medicines must be present in a medical product for the patient to receive therapeutic value. High performance liquid chromatography (HPLC) was used to develop a methodology to test for the API in Ampicillin and Cefuroxime drugs. Following the regulations of the Distributed Pharmaceutical Analysis Lab (DPAL) out of Notre Dame system sustainability requirements linearity, precision, accuracy/range, spike/degraded spike, limit of detection /quantitation, tailing factor, and number of theoretical plates were experimentally determined to meet the excepted standards.


Impact Of Urea On Size And Red-Edge Emission Spectroscopy Of Reverse Micelles, Tran Nguyen, Nancy E. Levinger, Bridget Gourley Ph.D Oct 2022

Impact Of Urea On Size And Red-Edge Emission Spectroscopy Of Reverse Micelles, Tran Nguyen, Nancy E. Levinger, Bridget Gourley Ph.D

Annual Student Research Poster Session

We use reverse micelles (RMs) as our model system to study the impact of osmolytes on water at the nanoscale. Reverse micelles are characterized by w0 = [polar component]/[surfactant]. In our experiment, we focus on 5 different w0 (w0 = 1, 5, 10, 20, 40) and 3 concentrations of urea (0.5M, 1M, 2M). The Dynamic Light Scattering (DLS) illustrates a linear relationship between reverse w0 (the ratio) and size. Additionally, the DLS data indicates that the impact of osmolytes on size for small reverse micelles is not significant. Furthermore, Red-Edge Emission Spectroscopy shows a bigger impact on emission for smaller …


Method Development For The Analysis Of Pharmaceuticals Using High Performance Liquid Chromatography, To Uyen (Anita) Nguyen, Richard Martoglio Ph.D Oct 2022

Method Development For The Analysis Of Pharmaceuticals Using High Performance Liquid Chromatography, To Uyen (Anita) Nguyen, Richard Martoglio Ph.D

Annual Student Research Poster Session

Since 2013, there have been 1500 reports of counterfeit drugs to WHO, especially from African, American, and European regions 1. Tackling the problem of poor drug quality, the Distributed Pharmaceutical Analysis Lab (DPAL) provides a quality analysis to quantify active pharmaceutical ingredient contents with a goal to trigger a report to the MRA or WHO2. With the support of DPAL, we would like to perform a series of chromatography experiments using the HPLC in order to identify and quantify the active pharmaceutical ingredients (API) of Amoxicillin and Ciprofloxacin.


Chemweb: A 2d Molecular Builder Game, Suleman Bashir Baloch, Jeff Hansen Ph.D Oct 2022

Chemweb: A 2d Molecular Builder Game, Suleman Bashir Baloch, Jeff Hansen Ph.D

Annual Student Research Poster Session

The research is based on the development of a 2D molecular builder game for CHEM 120 students. The game allows students to draw and check their structures for a given formula against a database of possible correct structures. The game consists of 8 levels, each based on drawing the maximum possible isomers from a given chemical formula. It is created as a web-based application on React.js. The project shall allow greater liberty and ease to students in drawing structures. In addition, they shall be able to perform self-check for drawn structures which will significantly minimize the assistance required from instructors …


Instrumental Analysis, David T. Harvey Jan 2022

Instrumental Analysis, David T. Harvey

Chemistry & Biochemistry Faculty Publications

Instrumental analysis is a field of analytical chemistry that investigates analytes using scientific instruments.