Chemistry Commons^™

Electrochemical Investigation Of Azurin Thermodynamic And Adsorption Properties At Monolayer-Protected Cluster Film Assemblies – Evidence For A More Homogeneous Adsorption Interface, Tran Doan, Morgan Lynn Vargo, John K. Gerig, Chris P. Gulka, Matthew L. Trawick, Jonathan D. Dattelbaum, Michael C. Leopold

Chemistry Faculty Publications

Thermodynamic and adsorption properties of protein monolayer electrochemistry (PME) are examined for Pseudomonas aeruginosa azurin (AZ) immobilized at an electrode modified with a networked film of monolayer-protected clusters (MPCs) to assess if nanoparticle films of this nature offer a more homogeneous adsorption interface compared to traditional self-assembled monolayer (SAM) modified electrodes. Specifically, electrochemistry is used to assess properties of surface coverage, formal potential, peak broadening, and electron transfer (ET) kinetics as a function of film thickness. The modification of a surface with dithiol-linked films of MPCs (Au225C675) provides a more uniform binding interface for AZ that results in voltammetry with …

Synthesis And Catalytic Activity Of Nanostructured Cerium Oxide, Neil J. Lawrence

Department of Chemistry: Dissertations, Theses, and Student Research

Cerium oxide (ceria, CeO_2-x where x is 0 to 0.5) has been one of the most widely used heterogeneous catalysts particularly in three way catalytic converters. Most of the catalytic traits can be attributed to two properties of ceria: first, the high mobility and storage capacity of oxygen within the lattice; second, the ease with which cerium changes between Ce³⁺ and Ce⁴⁺ states. These properties, combined with the abundance of cerium on earth, make ceria a low-cost highly effective alternative to noble metal catalysts. Recent research has been focused on the nanoscale properties of ceria.

The effect …

Enhanced Electrochemistry Of Nanoparticle-Embedded Polyelectrolyte Films: Interfacial Electronic Coupling And Distance Dependence, Callie E. Dowdy, Michael C. Leopold

Chemistry Faculty Publications

Factors affecting the electronic communication believed to be responsible for the enhanced solution electrochemistry observed at electrodes modified with hybrid polyelectrolyte–nanoparticle (PE–NP) film assemblies were systematically investigated. Specifically, the faradaic current and voltammetric peak splitting recorded for cyclic voltammetry of ferricyanide redox species (Fe(CN)63−/4−) at films constructed with various architectures of citrate-stabilized gold NPs embedded in polyelectrolyte films composed of poly-l-lysine and poly-S-styrene were used to establish the relative importance of both distance and electronic coupling. Layer-by-layer construction of PE–NP films allowed for the position and density of NPs to be varied within the film to assess electronic coupling between …

High Temperature Rare Earth Compounds: Synthesis, Characterization And Applications In Device Fabrication, Joseph R. Brewer

Department of Chemistry: Dissertations, Theses, and Student Research

As the area of nanotechnology continues to grow, the development of new nanomaterials with interesting physical and electronic properties and improved characterization techniques are several areas of research that will be remain vital for continued improvement of devices and the understanding in nanoscale phenomenon. In this dissertation, the chemical vapor deposition synthesis of rare earth (RE) compounds is described in detail. In general, the procedure involves the vaporization of a REClx (RE = Y, La, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho) in the presence of hydride phase precursors such as decaborane and ammonia at high temperatures and low …

Classification, Synthesis And Characterization Of Pyridyl Porphyrin Frameworks, Lucas D. Devries

Department of Chemistry: Dissertations, Theses, and Student Research

CLASSIFICATION, SYNTHESIS AND CHARACTERIZATION OF PYRIDYL PORPHYRIN FRAMEWORKS

Lucas D. DeVries, M.S. University of Nebraska, 2010 Adviser: Wonyoung Choe

Structural analysis of a solid-state material is vital because the structure often determines the physical (or chemical) properties of the material. An understanding of the relationship between structural components and bulk properties can be used to design materials with specific properties. To achieve such understanding, two things are required: a rigorous structural analysis method and a study of the properties of materials with noteworthy structural features.

In this thesis, the author reviews 44 pyridyl porphyrin frameworks in an effort to determine …

The Reaction Of A Water Soluble Platinum Compound With Methionine And Derivatives, Yueh Ying Liao

Masters Theses & Specialist Projects

Water soluble platinum complexes are a recent area of emphasis of cisplatin chemistry. The water soluble complexes could have a reduced toxicity compared with cisplatin. Oxaliplatin, which has an oxalate leaving group, has previously been shown to have less nephro-toxicity and higher water solubility than cisplatin. [Pt(en)(oxalate)] (en = ethylenediamine) has been prepared from Pt(en)Cl2 and silver oxalate. This complex has been reacted with methionine and N-acetylmethionine at different molar ratios. At high Pt: methionine ratios, chelates with the sulfur and nitrogen atoms of the methionine are dominant; at lower Pt: methionine ratios, a bis-methionine product is formed. The en …

Conformations Of A Model Protein Revealed By An Aggregating Cuᴵᴵ Porphyrin: Sensing The Difference, G. De Luca, A. Romeo, L. M. Scolaro, Robert F. Pasternack

Chemistry & Biochemistry Faculty Works

Aggregated t-CuP binds to poly-L-glutamate through supramolecular interactions, revealing itself to be an extremely sensitive probe for the major conformations of the polymeric scaffold.

Samuel J. Danishetsky And The Synthesis Of Globo-H Antigen, Chelsey Jones

Natural Sciences Student Research Presentations

Samuel J. Danishefsky is a research scientist at the Sloan-Kettering Institute. He uses his knowledge in organic chemistry to make biological advances in cancer research. Danishefsky has been conducting research and experiments on synthesizing anti-cancer vaccines with the use of carbohydrate antigens. Danishefsky has also been conducting research and experiments on homogeneous erythropoietin which could provide insight into how glycoproteins function. Knowledge of glycoprotein would allow scientists to better understand erythropoietin which can treat anemia in chemotherapy patients. All is valuable information in advances in cancer research and cancer research is important because it is a major disease affecting the …