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Characterization And Interactions Of Mercury, Dissolved Organic Matter And Organic Sulfur In Surface Waters Of The Florida Everglades, Maria Asuncion Calero Sheils
Characterization And Interactions Of Mercury, Dissolved Organic Matter And Organic Sulfur In Surface Waters Of The Florida Everglades, Maria Asuncion Calero Sheils
FIU Electronic Theses and Dissertations
Two sampling stations in the Florida Everglades were selected based on the results from US Environmental Protection Agency and Florida International University Mercury Project. In both sites, most of the methylmercury is associated with the truly dissolved organic matter fraction (
Targeting Of Ribonucleotide Reductase With 2'-Disulfide Analogs Of Adenosine. Electronic Versus Steric Effects In Radical Deoxygenation Of Fluorine-Containing Nucleosides, Dania Companioni
FIU Electronic Theses and Dissertations
Inhibition of the enzyme ribonucleotide reductase is an appealing concept for the rational drug design against rapid proliferation of systems such as viruses and cancer cells. Synthesis of 2'-thionucleoside analogs as possible inhibitors of the enzyme was targeted in this research. For protecting the reactive thiol group, mixed disulfides were prepared as precursors of the sulfur-containing nucleosides. The thionucleoside obtained are currently under biological studies.
Fluorinated compounds are widely used in biochemistry, medicinal chemistry, and pharmacology. Synthesis of 2'-deoxy-2'-fluoroadenosine and its arabino epimer as well as 3’-deoxy-3'-fluoroadenosine and its xylo epimer were also targeted in order to study the electronic …