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Missouri University of Science and Technology
<p>Brain<br />Nanoparticles<br />Nervous system -- Degeneration -- Research<br />Oxidative stress -- Health aspects</p>
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Full-Text Articles in Chemistry
Nano-Particles Induced Oxidative Stress In Immortalized Human Brain Endothelial Cells, Xinsheng Zhang
Nano-Particles Induced Oxidative Stress In Immortalized Human Brain Endothelial Cells, Xinsheng Zhang
Doctoral Dissertations
"Nanoparticles are engineered structure with at least one dimension of 100 nanometers or less. These materials are increasingly being used for commercial purposes such as catalyst, semiconductor, cosmetics, microelectronic, and drug carrier. However, the toxicological impact of these materials has not yet been studied in detail, thereby limiting their use. In our present study, we use human brain endothelial cell line as a blood-brain barrier (BBB) model to investigate if two kinds of nanoparticles [ 1). Diesel exhaust particles (DEPs) and 2). single wall carbon nanotube (CNT) ] induced oxidative stress in cell model. Our studies showed that DEPs or …