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Missouri University of Science and Technology

Masters Theses

<p>Hydroxy acids<br />Trace analysis -- Methodology<br />Mass spectrometry<br />Chromatographic analysis<br />Gas chromatography<br />Liquid chromatography</p>

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A Rapid Method For Determination Of Alpha Hydroxy Acids In Seawater And Biological Fluids At Trace Levels, Ryan Lee Schwiderski Jan 2008

A Rapid Method For Determination Of Alpha Hydroxy Acids In Seawater And Biological Fluids At Trace Levels, Ryan Lee Schwiderski

Masters Theses

"Alpha hydroxy acids (AHAs) - carboxylic acids with a hydroxyl substitution on the alpha carbon are an important class of molecules. Hydroxy Methyl Thiobutanoic Acid (HMTBA) is an α-hydroxy analog of essential amino acid methionine; it finds extensive use as a feed supplement for avian and bovine species. Efficacy of alpha hydroxy acid uptake is important for nutritional studies and such studies rely on accurate and precise methods for determination of these chemicals in biological samples. Several methods for AHAs determination have been reported, however, the methods are tedious, requiring multiple sample preparation steps. Experiments reported in this thesis were …