Chemistry Commons^™

Ligand-Receptor Interactions For Supramolecular Disassembly With Applications In Screening And Drug Delivery, Diego Amado Torres

Doctoral Dissertations

Proteins have the capacity to bind specific sets of compounds known as ligands, these are small molecules with a recurrent theme in their molecular design that is a characteristic exploited here to (i) identify particular affinities of small molecules for proteins with the aim of using them as ligands, inhibitors, or targeting moieties in more complex systems by means of a methodology that screens small molecules based on protein affinity; (ii) decorate a self-assembling supramolecular system at different positions, making it responsive to a complementary protein with the aim of exploring differences in disassembly and sensitivity of the release of …

The Surface Chemistry Of Adatom Mediated Oligomers Of Aromatic Diisocyanides And Dithiols On Au(111) And Granular Films, John Kestell

Theses and Dissertations

Abstract

The Surface Chemistry of Adatom Mediated Oligomers

of Aromatic Diisocyanides and Dithiols on Au(111) and Granular Films

by

John D. Kestell

The University of Wisconsin-Milwaukee

Under the supervision of Professor W. T. Tysoe

Two seminal events are thought by many to be the birth of nanotechnology and molecular electronics. In 1959, Nobel Laureate Richard Feynman gave his famous "There's Plenty of Room at the Bottom" lecture to an American Physical Society meeting at Caltech. The transistor had been invented by Bell Laboratories in 1947, and already the race was on for device miniaturization. Feynman's lecture focused on some of …

Synthesis And Characterization Of Coloumnar Mesophases Of Novel Substituted Dibenzanthracenes And Their Donor-Acceptor Mixtures, Katie M. Psutka

Theses and Dissertations (Comprehensive)

In this thesis, the synthesis and liquid crystalline properties of a series of novel dibenz[a,c]anthracenes are reported. Specifically, two dibenzanthracenecarboxylate derivatives were prepared and were found not to exhibit a mesophase. In contrast, a series of novel N-substituted dibenzanthracenedicarboximides was also synthesized and found to exhibit broad columnar temperature ranges. Several dibenzanthracenedicarboximides substituted with different alkyl chains on the nitrogen atom were prepared and their mesomorphic temperature ranges were characterized. In general, it was found that having a longer, more flexible alkyl chain on the nitrogen atom resulted in a broadening of the columnar temperature range via a lowering …