Chemistry Commons^™

Functionalization Of Resorcinarenes And Study Of Antimicrobial Activity, Kirankirti Muppalla

USF Tampa Graduate Theses and Dissertations

Cavitands are very important class of compounds in supramolecular chemistry. These molecules contain rigid enforced cavity,and have attracted considerable attention in supramolecular chemistry as building blocks for the construction of carcerands, hemicarcerands, and other host guests complexes. Nearly 40 years ago, Niederl and Vogel laid foundation for the study of such type of condensation reactions. In our laboratory we are involved in synthesis of resorcinarenes with readily available substrates such as resorcinol and aldehydes to form a cyclic tetramer.

Herein, I present detailed studies about the functionalization of the synthesized tetramers and their antimicrobial activity. Octahydroxy resorcinarenes were synthesized and …

The Extent Of Perturbation Of Skin Models By Transdermal Penetration Enhancers Investigated By 31p Nmr And Fluorescence Spectroscopy, Charmita Patricia Burch

Chemistry Dissertations

The molecular basis of the potent transdermal enhancement activity of a series of iminosulfuranes, structure provided where X = H, Cl, Br, and I, is being investigated skin models. It has been shown (J. Lipid Res. 46(2005), 2192-2201.) that correlations exist between the activity of the aforementioned transdermal penetration enhancers (TPE) and the extent to which these agents bind to DMPC vesicles and perturb the gel to liquid crystal phase transition measured by calorimetry. The degree to which the perturbation of these compounds extends into the bilayer interior in contrast to surface activity is unclear. To gain insight into this …

Tailoring Branching For Poly (Arylene Ether)S Via Reactivity Ratio Controlled Polymerizations, Amanda Ike

Browse all Theses and Dissertations

The ability to control physical and mechanical properties of polymer systems has become an important aspect of polymer science. In order to tailor the branching in polymer systems, an understanding into the reactivity of the electrophilic sites in the monomer is important. Kinetic methods have been explored in order to determine the reactivity of monomers in preparing poly(arylene ether)s and to predict the degree of branching that will occur in a polymer of this kind. The reactivity of AB2 sulfones and phosphine oxides was explored, along with the reactivity of ABB'B'' sulfones. NMR spectroscopy was used as a probe into …

Probing The Association Behavior Of Hydrophobic Organic Compounds With Dissolved Humic Materials, Hadi M. Marwani

LSU Doctoral Dissertations

The association mechanism between hydrophobic organic compounds (HOC) and dissolved humic materials (DHM) has continued to be one of the interesting areas in environmental applications. The goal of the research reported in this dissertation is to investigate the association behavior of HOC with DHM. The first part of this research involves steady-state fluorescence measurements of these multi-component systems to study the effect of DHM content on the association mechanism of HOC, in particular using pyrene as a model. Results showed that steady-state fluorescence alone may not provide enough information about the quenching mechanism of pyrene with DHM. Lifetime based fluorescence …