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Full-Text Articles in Chemistry

Phytochemical Constituent And Antioxidant Activity Evaluation Of Red Seaweed Eucheuma Sp., Ade Arsianti Oct 2023

Phytochemical Constituent And Antioxidant Activity Evaluation Of Red Seaweed Eucheuma Sp., Ade Arsianti

Indonesian Journal of Medical Chemistry and Bioinformatics

Oxidative stress is a condition in which there is an imbalance between production of free radicals and protective response via antioxidant system. There are endogenous and exogenous antioxidants, however as age increases, there is a reduction in endogenous antioxidant, thus the search for potential exogenous antioxidants which could be derived from natural resources are needed. Indonesia is a megabiodiversity country which has more than 30,000 species of plants and animals. Red seaweed Eucheuma sp. is one of marine macroalgae species which shows potent biological activities. This study aims to determine the phytochemical constituent and to evaluate the antioxidant activity of …


Study Of Antioxidant Activity Of The Derivatives Of Quinoline-4-Carboxylic Acids By The Modification Of Isatin Via Pfitzinger Reaction, Sakti Hidayati Fikriya, Antonius Herry Cahyana Jun 2023

Study Of Antioxidant Activity Of The Derivatives Of Quinoline-4-Carboxylic Acids By The Modification Of Isatin Via Pfitzinger Reaction, Sakti Hidayati Fikriya, Antonius Herry Cahyana

Makara Journal of Science

In this study, a quinoline-4-carboxylic acid derivative was synthesized through Pfitzinger reaction. In this reaction, isatin is modified via its reaction with ketone and refluxed for 24 h to obtain quinoline-4-carboxylic acid. The presence of a carboxylic group was identified by Fourier Transform Infrared (FTIR) spectroscopy and ultraviolet–visible (UV-Vis) spectrophotometry. The results showed that the absorption peaks of C=O and O–H stretching’s were detected in the range of 1724–1708 and 3436–3242 cm−1, respectively. In the UV-vis spectrum, a shift in the absorption peak was observed toward a larger wavelength, which is referred as a bathochromic shift. The formation …