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Synthesis And Characterization Of Anderson-Evans Type Polyoxometalates, Antibacterial Properties, Hülya Avci Özbek
Synthesis And Characterization Of Anderson-Evans Type Polyoxometalates, Antibacterial Properties, Hülya Avci Özbek
Turkish Journal of Chemistry
In the present work, the new aluminium-substituted polyoxometalates of the Anderson-Evans type have been prepared and structurally defined by the reaction of aluminium (III) chloride hexahydrate and sodium tungstate dihydrate/sodium molybdate dihydrate in an aqueous basic medium. Elemental analysis, FT-IR, TGA, 1H NMR, and 31P NMR analysis revealed that these polyoxometalates had the following formula: [Ph4 P]3 [Al(OH)6 Mo6 O18]·4H2 O 1, [Ph4 P]3 [Al(OH)6 W6 O18]·4H2 O 2, [C7 H10N]3 [Al(OH)6 Mo6 O18]·4H2 O 3, [C7 H10N]3 [Al(OH)6 W6 O18]·4H2 O 4. The compounds 1 and 2 show promising antibacterial activity against gram-positive Staphylcoccus aureus ATCC 25923 and gram-negative …
Synthesis, Molecular Simulation Studies, In Vitro Biological Assessment Of 2-Substituted Benzoxazole Derivatives As Promising Antimicrobial Agents, Gajanan S. Shanbhan, Amit Bhargava, Giridhar Pal Singh, Shrinivas D. Joshi, Narendra Chundawat
Synthesis, Molecular Simulation Studies, In Vitro Biological Assessment Of 2-Substituted Benzoxazole Derivatives As Promising Antimicrobial Agents, Gajanan S. Shanbhan, Amit Bhargava, Giridhar Pal Singh, Shrinivas D. Joshi, Narendra Chundawat
Turkish Journal of Chemistry
The 2-substituted benzoxazole derivatives are known to exhibit a wide spectrum of biological potential. Two series of novel benzoxazole derivatives containing 2-phenyl and 2-N-phenyl groups were synthesized, by following the green chemistry approach. All the newly synthesized derivatives were screened against gram-positive bacteria (Streptococcus pyogenes, Staphylococcus aureus), gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli) and the fungus (Aspergillus clavatus and Candida albicans). Most of these compounds have demonstrated potent antibacterial activities, especially against E. coli at 25 μg/mL, along with moderate antifungal activity. Among these, two compounds, 21 and 18, showed interesting antibacterial profile. Molecular …