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The Application Of Stereolithography To The Creation Of Molecular Models Of Amiloride And Its Analogues, Thomas John Busanic
The Application Of Stereolithography To The Creation Of Molecular Models Of Amiloride And Its Analogues, Thomas John Busanic
Theses
Stereolithography, a process by which a computer-guided Ultraviolet (UV) laser is applied onto a liquid monomer resin to form a solid polymer, was used to create solid models of amiloride and two of its analogues. The Cartesian coordinates used as input for the orientation of each atom in a molecule were calculated using ab initio molecular orbital theory. Since the structures of the molecules are calculated in this fashion, they represent a more accurate representation of the molecules than that provided by standard molecular modeling kits.
The original purpose of this work was to assist a blind chemist in appreciating …